Genetic evidence for amlodipine's protective role in gastroesophageal reflux disease: A focus on CACNB2.

Genetic evidence for amlodipine's protective role in gastroesophageal reflux disease: A focus on CACNB2.

<h4>Objective</h4>This study aims to elucidate the causal relationship between genetically predicted amlodipine use and the risk of gastroesophageal reflux disease (GERD) using a bidirectional Mendelian Randomization (MR) approach and to explore the underlying genetic and molecular mecha...

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Bibliographic Details
Main Authors: Liuzhao Zhang, Quanwang Chu, Shuyue Jiang, Bo Shao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0309805
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