Identification of the role of SNARE proteins in rAAV vector production through interaction with the viral MAAP

Adeno-associated virus (AAV) expresses a membrane-associated accessory protein (MAAP), a small nonstructural protein, that facilitates AAV secretion out of the plasma membrane through an association with extracellular vesicles during AAV egress. Here, we investigated the host proteins that interact...

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Bibliographic Details
Main Authors: Cagla Aksu Kuz, Kang Ning, Siyuan Hao, Shane McFarlin, Xiujuan Zhang, Fang Cheng, Jianming Qiu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Molecular Therapy: Methods & Clinical Development
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Online Access:http://www.sciencedirect.com/science/article/pii/S2329050124002080
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