Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247

ABSTRACT The bioproduction of selenium nanoparticles (SeNPs) is garnering increasing attention as an environmentally friendly method, given that many microorganisms inherently possess the ability to synthesize nano‐selenium. In the present study, Lactobacillus bulgaricus (L. bulgaricus) was selected...

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Main Authors: Yebo Wang, Ke Li, Wenting Zhu, Huijuan Xi, Meng Qi, Ping Chen, Hanyu Chen, Chun‐e Zhang, Ying Luo
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:eFood
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Online Access:https://doi.org/10.1002/efd2.70074
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author Yebo Wang
Ke Li
Wenting Zhu
Huijuan Xi
Meng Qi
Ping Chen
Hanyu Chen
Chun‐e Zhang
Ying Luo
author_facet Yebo Wang
Ke Li
Wenting Zhu
Huijuan Xi
Meng Qi
Ping Chen
Hanyu Chen
Chun‐e Zhang
Ying Luo
author_sort Yebo Wang
collection DOAJ
description ABSTRACT The bioproduction of selenium nanoparticles (SeNPs) is garnering increasing attention as an environmentally friendly method, given that many microorganisms inherently possess the ability to synthesize nano‐selenium. In the present study, Lactobacillus bulgaricus (L. bulgaricus) was selected to convert sodium selenite to SeNPs, the optimum conversion conditions were finally established, the morphology and structure of SeNPs were characterized as uniform distribution spherical particles with average size of 92.4 nm, in combination with field emission scanning electron microscope (FE‐SEM), transmission electron microscope (TEM), X‐ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopy (FTIR). 16S rDNA sequencing and genomic sequencing revealed that SeNPs influenced the composition of the gut microbiota, the abilities of immune and metabolism in mice were improved significantly after SeNPs supplement. The results corroborated the potential of SeNPs synthesized from probiotic L. bulgaricus CICC 20247 in intestinal health promotion and various biomedical even food processing applications.
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institution Kabale University
issn 2666-3066
language English
publishDate 2025-08-01
publisher Wiley
record_format Article
series eFood
spelling doaj-art-1dd2b95c30424cd582990ff03035b7cc2025-08-20T03:36:26ZengWileyeFood2666-30662025-08-0164n/an/a10.1002/efd2.70074Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247Yebo Wang0Ke Li1Wenting Zhu2Huijuan Xi3Meng Qi4Ping Chen5Hanyu Chen6Chun‐e Zhang7Ying Luo8College of Food Engineering and Nutritional Science Shaanxi Normal University Xi'an Shaanxi ChinaCollege of Food Engineering and Nutritional Science Shaanxi Normal University Xi'an Shaanxi ChinaCollege of Food Engineering and Nutritional Science Shaanxi Normal University Xi'an Shaanxi ChinaCollege of Food Engineering and Nutritional Science Shaanxi Normal University Xi'an Shaanxi ChinaKey Laboratory of Se‐enriched Products Development and Quality Control, Ankang Research and Development Center for Se‐enriched Products Ministry of Agriculture and Rural Affairs Ankang Shaanxi ChinaCollege of Food Engineering and Nutritional Science Shaanxi Normal University Xi'an Shaanxi ChinaCollege of Food Engineering and Nutritional Science Shaanxi Normal University Xi'an Shaanxi ChinaNingxia Hui Autonomous Region Grain and Oil Product Quality Inspection Center Yinchuan ChinaCollege of Food Engineering and Nutritional Science Shaanxi Normal University Xi'an Shaanxi ChinaABSTRACT The bioproduction of selenium nanoparticles (SeNPs) is garnering increasing attention as an environmentally friendly method, given that many microorganisms inherently possess the ability to synthesize nano‐selenium. In the present study, Lactobacillus bulgaricus (L. bulgaricus) was selected to convert sodium selenite to SeNPs, the optimum conversion conditions were finally established, the morphology and structure of SeNPs were characterized as uniform distribution spherical particles with average size of 92.4 nm, in combination with field emission scanning electron microscope (FE‐SEM), transmission electron microscope (TEM), X‐ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopy (FTIR). 16S rDNA sequencing and genomic sequencing revealed that SeNPs influenced the composition of the gut microbiota, the abilities of immune and metabolism in mice were improved significantly after SeNPs supplement. The results corroborated the potential of SeNPs synthesized from probiotic L. bulgaricus CICC 20247 in intestinal health promotion and various biomedical even food processing applications.https://doi.org/10.1002/efd2.70074characteristics analysisgut microbiotaselenium nanoparticles (SeNPs)transcriptome sequencing
spellingShingle Yebo Wang
Ke Li
Wenting Zhu
Huijuan Xi
Meng Qi
Ping Chen
Hanyu Chen
Chun‐e Zhang
Ying Luo
Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247
eFood
characteristics analysis
gut microbiota
selenium nanoparticles (SeNPs)
transcriptome sequencing
title Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247
title_full Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247
title_fullStr Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247
title_full_unstemmed Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247
title_short Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247
title_sort characteristics analysis and intestinal effects of probiotic derived nano selenium by lactobacillus bulgaricus cicc 20247
topic characteristics analysis
gut microbiota
selenium nanoparticles (SeNPs)
transcriptome sequencing
url https://doi.org/10.1002/efd2.70074
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