The role of Anvillea garcinii and its compounds in health and disease: An overview

Objective: This scoping review aims to examine the potential health benefits of Anvillea garcinii and its compounds and provide recommendations based on available research. A. garcinii is a plant species in the daisy family that has demonstrated several therapeutic and preventive effects.Materials a...

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Main Authors: Ali Zarei, Fatemeh Rasekh, Samaneh Ahmadpour Khorrami, Behnam Masmouei, Saeed Changizi-Ashtiyani, Majid Ramezani, Amirhossein Zarei
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-06-01
Series:Avicenna Journal of Phytomedicine
Subjects:
Online Access:https://ajp.mums.ac.ir/article_25131_b9daa15b404bacae186463022e7d4857.pdf
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author Ali Zarei
Fatemeh Rasekh
Samaneh Ahmadpour Khorrami
Behnam Masmouei
Saeed Changizi-Ashtiyani
Majid Ramezani
Amirhossein Zarei
author_facet Ali Zarei
Fatemeh Rasekh
Samaneh Ahmadpour Khorrami
Behnam Masmouei
Saeed Changizi-Ashtiyani
Majid Ramezani
Amirhossein Zarei
author_sort Ali Zarei
collection DOAJ
description Objective: This scoping review aims to examine the potential health benefits of Anvillea garcinii and its compounds and provide recommendations based on available research. A. garcinii is a plant species in the daisy family that has demonstrated several therapeutic and preventive effects.Materials and Methods: This review was conducted with a comprehensive approach. We meticulously searched multiple databases, including PubMed, Embase, Scopus, Cochrane, SID, and Magiran, using the keyword "A. garcinii " on October 4, 2023.Results: Research suggests that A. garcinii extract possesses several properties that could benefit health. These include anti-hyperglycemic, anti-hyperlipidemic, and anti-inflammatory activities. The extract also displays anti-oxidant properties, enhances insulin sensitivity, and inhibits α-amylase and α-glucosidase. Additionally, it exhibits hepatoprotective activity, cytotoxic activity against cancerous cells, anti-fungal, anti-human immunodeficiency virus (HIV), anti-bacterial, anti-cholinesterase, and anti-tyrosinase activities.Conclusion: The diverse health benefits of A. garcinii extract and its active compounds, such as germacranolide and parthenolide, present significant potential for use in the food, cosmetic, and pharmaceutical industries. This potential, especially in treating diabetes, gastric ulcers, and cancer, opens up exciting possibilities for the future.
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spelling doaj-art-1dc4694e24544eca966cb94da85b45d92025-08-20T01:51:24ZengMashhad University of Medical SciencesAvicenna Journal of Phytomedicine2228-79302228-79492025-06-011531113112310.22038/ajp.2024.2513125131The role of Anvillea garcinii and its compounds in health and disease: An overviewAli Zarei0Fatemeh Rasekh1Samaneh Ahmadpour Khorrami2Behnam Masmouei3Saeed Changizi-Ashtiyani4Majid Ramezani5Amirhossein Zarei6Department of Physiology, Estahban School of Paramedical Sciences, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Biology, Payam Noor University of Tehran, Tehran, IranDepartment of Chemical Engineering, Shiraz Branch, Islamic Azad University, Shiraz, IranDepartment of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Physiology, Iran University of Medical Sciences, Tehran, IranDepartment of Internal Medicine, Baqiyatallah University of Medical Sciences, Tehran, IranDepartment of Education, Abadeh Vesal High School, Abadeh, IranObjective: This scoping review aims to examine the potential health benefits of Anvillea garcinii and its compounds and provide recommendations based on available research. A. garcinii is a plant species in the daisy family that has demonstrated several therapeutic and preventive effects.Materials and Methods: This review was conducted with a comprehensive approach. We meticulously searched multiple databases, including PubMed, Embase, Scopus, Cochrane, SID, and Magiran, using the keyword "A. garcinii " on October 4, 2023.Results: Research suggests that A. garcinii extract possesses several properties that could benefit health. These include anti-hyperglycemic, anti-hyperlipidemic, and anti-inflammatory activities. The extract also displays anti-oxidant properties, enhances insulin sensitivity, and inhibits α-amylase and α-glucosidase. Additionally, it exhibits hepatoprotective activity, cytotoxic activity against cancerous cells, anti-fungal, anti-human immunodeficiency virus (HIV), anti-bacterial, anti-cholinesterase, and anti-tyrosinase activities.Conclusion: The diverse health benefits of A. garcinii extract and its active compounds, such as germacranolide and parthenolide, present significant potential for use in the food, cosmetic, and pharmaceutical industries. This potential, especially in treating diabetes, gastric ulcers, and cancer, opens up exciting possibilities for the future.https://ajp.mums.ac.ir/article_25131_b9daa15b404bacae186463022e7d4857.pdfanvillea garciniahealthanti-oxidantdiabetescancer
spellingShingle Ali Zarei
Fatemeh Rasekh
Samaneh Ahmadpour Khorrami
Behnam Masmouei
Saeed Changizi-Ashtiyani
Majid Ramezani
Amirhossein Zarei
The role of Anvillea garcinii and its compounds in health and disease: An overview
Avicenna Journal of Phytomedicine
anvillea garcinia
health
anti-oxidant
diabetes
cancer
title The role of Anvillea garcinii and its compounds in health and disease: An overview
title_full The role of Anvillea garcinii and its compounds in health and disease: An overview
title_fullStr The role of Anvillea garcinii and its compounds in health and disease: An overview
title_full_unstemmed The role of Anvillea garcinii and its compounds in health and disease: An overview
title_short The role of Anvillea garcinii and its compounds in health and disease: An overview
title_sort role of anvillea garcinii and its compounds in health and disease an overview
topic anvillea garcinia
health
anti-oxidant
diabetes
cancer
url https://ajp.mums.ac.ir/article_25131_b9daa15b404bacae186463022e7d4857.pdf
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