The immunogenicity of PRV ΔgE/TK/UL49.5 three-gene-deleted vaccine in mice

The immunogenicity of PRV ΔgE/TK/UL49.5 three-gene-deleted vaccine in mice

Abstract Background Pseudorabies (PR) caused by the re-emerging of pseudorabies virus (PRV) variant has outbroken among PRV vaccine immunized swine in many pig farms, which has caused serious social and economic consequences since the end of 2011. The PRV UL49.5 protein can inactivate the transporte...

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Bibliographic Details
Main Authors: Chenmeng Ding, Yawei Sun, Xianfeng Zhang, Mengmeng Shi, Han Yang, Xin Zhou, Shuangshuang Li, Yongtao Li, Xia Yang, Linyang Yu, Lu Chen
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Virology Journal
Subjects:
Pseudorabies virus
gE/TK/UL49.5 deletion
Safety
Immunogenicity
Online Access:https://doi.org/10.1186/s12985-025-02641-w
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