Staphylococcus epidermidis uses the SrrAB regulatory system to modulate oxidative stress and intracellular survival in mouse macrophage cell line Ana-1

Staphylococcus epidermidis uses the SrrAB regulatory system to modulate oxidative stress and intracellular survival in mouse macrophage cell line Ana-1

ABSTRACT The two-component system (TCS) SrrAB responds to oxidative stress in Staphylococcus epidermidis. A srrAB deletion mutant (∆srrAB) was constructed using S. epidermidis strain 1457 (SE1457) as the parent strain to study its regulatory function in oxidative stress. Compared to SE1457, the viab...

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Bibliographic Details
Main Authors: Chunjing Zhao, Zongkai Bai, Xiaoting Chen, Shuangjie Shang, Baitong Shen, Li Bai, Di Qu, Yang Wu, Youcong Wu
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSystems
Subjects:
Staphylococcal respiratory response
Staphylococcus epidermidis
oxidative stress
macrophage
ROS
Online Access:https://journals.asm.org/doi/10.1128/msystems.01737-24
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