SPTBN1 overexpression ameliorates atherosclerosis by inhibiting oxidative stress and inflammation via regulating the TRIM37/TRAF2/NF-κB pathway
Abstract Background Endothelial cell apoptosis and oxidative stress are pivotal drivers of atherosclerosis (AS) progression. It was revealed that spectrin beta, non-erythrocytic 1 (SPTBN1) levels were remarkably decreased in the atherosclerotic plaque vessels of advanced lesions. This study aimed to...
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| Main Authors: | Senyan Wu, Xiaoni Tan, Guobing Cheng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | European Journal of Medical Research |
| Online Access: | https://doi.org/10.1186/s40001-025-02994-6 |
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