Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures

Occult hepatitis B infection (OBI) is a serious public health issue. Although a number of effective hepatitis B vaccines are available, hepatitis B still poses a threat to global public health. Patients with OBI are usually asymptomatic, but there may be active HBV DNA present in their blood, leadin...

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Main Authors: Meng Yi, Shuchang Dai, Lin Fang, Bo Pan, Bin Fan, Yiming Pan, Zhong Liu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/14/4/301
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author Meng Yi
Shuchang Dai
Lin Fang
Bo Pan
Bin Fan
Yiming Pan
Zhong Liu
author_facet Meng Yi
Shuchang Dai
Lin Fang
Bo Pan
Bin Fan
Yiming Pan
Zhong Liu
author_sort Meng Yi
collection DOAJ
description Occult hepatitis B infection (OBI) is a serious public health issue. Although a number of effective hepatitis B vaccines are available, hepatitis B still poses a threat to global public health. Patients with OBI are usually asymptomatic, but there may be active HBV DNA present in their blood, leading to the risk of virus transmission during blood transfusions or organ transplantation, constituting a hazard to the health of recipients and increasing the risk of liver cirrhosis and liver cancer. Although China has progressed in the development of blood-screening technology, OBI is still a significant hidden danger to blood transfusion safety. Therefore, in blood screening and blood transfusion, strengthening the monitoring and management of OBI is crucial to ensure blood safety and protect public health.
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publishDate 2025-03-01
publisher MDPI AG
record_format Article
series Pathogens
spelling doaj-art-1db43660aaba4ea79ec7e7b8f2292e852025-08-20T02:18:04ZengMDPI AGPathogens2076-08172025-03-0114430110.3390/pathogens14040301Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its CountermeasuresMeng Yi0Shuchang Dai1Lin Fang2Bo Pan3Bin Fan4Yiming Pan5Zhong Liu6Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Peking Union Medical College, Chengdu 610052, ChinaInstitute of Blood Transfusion, Chinese Academy of Medical Sciences, Peking Union Medical College, Chengdu 610052, ChinaInstitute of Blood Transfusion, Chinese Academy of Medical Sciences, Peking Union Medical College, Chengdu 610052, ChinaInstitute of Blood Transfusion, Chinese Academy of Medical Sciences, Peking Union Medical College, Chengdu 610052, ChinaInstitute of Blood Transfusion, Chinese Academy of Medical Sciences, Peking Union Medical College, Chengdu 610052, ChinaInstitute of Blood Transfusion, Chinese Academy of Medical Sciences, Peking Union Medical College, Chengdu 610052, ChinaInstitute of Blood Transfusion, Chinese Academy of Medical Sciences, Peking Union Medical College, Chengdu 610052, ChinaOccult hepatitis B infection (OBI) is a serious public health issue. Although a number of effective hepatitis B vaccines are available, hepatitis B still poses a threat to global public health. Patients with OBI are usually asymptomatic, but there may be active HBV DNA present in their blood, leading to the risk of virus transmission during blood transfusions or organ transplantation, constituting a hazard to the health of recipients and increasing the risk of liver cirrhosis and liver cancer. Although China has progressed in the development of blood-screening technology, OBI is still a significant hidden danger to blood transfusion safety. Therefore, in blood screening and blood transfusion, strengthening the monitoring and management of OBI is crucial to ensure blood safety and protect public health.https://www.mdpi.com/2076-0817/14/4/301occult hepatitis B infectionsafety of blood transfusionHBVvoluntary blood donation
spellingShingle Meng Yi
Shuchang Dai
Lin Fang
Bo Pan
Bin Fan
Yiming Pan
Zhong Liu
Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures
Pathogens
occult hepatitis B infection
safety of blood transfusion
HBV
voluntary blood donation
title Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures
title_full Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures
title_fullStr Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures
title_full_unstemmed Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures
title_short Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures
title_sort influence of occult hepatitis b infection on blood transfusion safety and its countermeasures
topic occult hepatitis B infection
safety of blood transfusion
HBV
voluntary blood donation
url https://www.mdpi.com/2076-0817/14/4/301
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