Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus
Objective To explore the saccadic wave parameters of patients with spontaneous nystagmus (SN) and head-shaking nystagmus (HSN) by developing a new quantitative assessment software, so as to reveal the saccadic characteristics and variations in patients with vestibular dysfunction across different co...
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Editorial Office of Journal of Guangxi Medical University
2024-10-01
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| Series: | Guangxi Yike Daxue xuebao |
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| Online Access: | https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.10.010 |
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| author | DU Yi LIU Xingjian WANG Yu XU Zhengyan REN Lili WU Ziming |
| author_facet | DU Yi LIU Xingjian WANG Yu XU Zhengyan REN Lili WU Ziming |
| author_sort | DU Yi |
| collection | DOAJ |
| description | Objective To explore the saccadic wave parameters of patients with spontaneous nystagmus (SN) and head-shaking nystagmus (HSN) by developing a new quantitative assessment software, so as to reveal the saccadic characteristics and variations in patients with vestibular dysfunction across different compensatory states. Methods A retrospective analysis was conducted on clinical data of patients from the Dizziness Treatment Center of the First Medical Center of the Chinese PLA General Hospital between September 2023 and June 2024. The"Saccades All in One (v1.0)"software, developed in-house, was used to process the raw data from the video head impulse test (vHIT). Detailed analyses of saccadic wave parameters were performed for patients in the SN, HSN, and non-nystagmus (None) groups. Results In the SN and HSN groups, the affected side showed significantly higher counts, amplitudes, and gains in the first and second saccadic waves compared to the unaffected side. With the progression of compensation, the number and amplitude of saccades on the affected side gradually decreased, and their latencies were earlier, whereas changes on the unaffected side were not pronounced. Statistical analyses further confirmed significant differences in saccadic parameters among the three groups, especially in terms of saccades count and amplitude. Conclusion The quantitative tool developed in this study effectively evaluates and distinguishes the characteristics of saccades in compensated and uncompensated states, thereby facilitating the diagnosis and treatment of patients with vestibular dysfunction. |
| format | Article |
| id | doaj-art-1da9cb9a567446e8b2cb3ca4f87f36ec |
| institution | OA Journals |
| issn | 1005-930X |
| language | zho |
| publishDate | 2024-10-01 |
| publisher | Editorial Office of Journal of Guangxi Medical University |
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| series | Guangxi Yike Daxue xuebao |
| spelling | doaj-art-1da9cb9a567446e8b2cb3ca4f87f36ec2025-08-20T02:15:23ZzhoEditorial Office of Journal of Guangxi Medical UniversityGuangxi Yike Daxue xuebao1005-930X2024-10-0141101378138310.16190/j.cnki.45-1211/r.2024.10.010gxykdxxb-41-10-1378Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmusDU Yi0LIU Xingjian1WANG Yu2XU Zhengyan3REN Lili4WU Ziming5The First Medical Center of the Chinese PLA General Hospital, Beijing 100853, ChinaThe First Medical Center of the Chinese PLA General Hospital, Beijing 100853, ChinaThe First Medical Center of the Chinese PLA General Hospital, Beijing 100853, ChinaThe First Medical Center of the Chinese PLA General Hospital, Beijing 100853, ChinaThe First Medical Center of the Chinese PLA General Hospital, Beijing 100853, ChinaThe First Medical Center of the Chinese PLA General Hospital, Beijing 100853, ChinaObjective To explore the saccadic wave parameters of patients with spontaneous nystagmus (SN) and head-shaking nystagmus (HSN) by developing a new quantitative assessment software, so as to reveal the saccadic characteristics and variations in patients with vestibular dysfunction across different compensatory states. Methods A retrospective analysis was conducted on clinical data of patients from the Dizziness Treatment Center of the First Medical Center of the Chinese PLA General Hospital between September 2023 and June 2024. The"Saccades All in One (v1.0)"software, developed in-house, was used to process the raw data from the video head impulse test (vHIT). Detailed analyses of saccadic wave parameters were performed for patients in the SN, HSN, and non-nystagmus (None) groups. Results In the SN and HSN groups, the affected side showed significantly higher counts, amplitudes, and gains in the first and second saccadic waves compared to the unaffected side. With the progression of compensation, the number and amplitude of saccades on the affected side gradually decreased, and their latencies were earlier, whereas changes on the unaffected side were not pronounced. Statistical analyses further confirmed significant differences in saccadic parameters among the three groups, especially in terms of saccades count and amplitude. Conclusion The quantitative tool developed in this study effectively evaluates and distinguishes the characteristics of saccades in compensated and uncompensated states, thereby facilitating the diagnosis and treatment of patients with vestibular dysfunction.https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.10.010spontaneous nystagmushead-shaking nystagmussaccadic wavevestibular function assessmentvideo head impulse test |
| spellingShingle | DU Yi LIU Xingjian WANG Yu XU Zhengyan REN Lili WU Ziming Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus Guangxi Yike Daxue xuebao spontaneous nystagmus head-shaking nystagmus saccadic wave vestibular function assessment video head impulse test |
| title | Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus |
| title_full | Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus |
| title_fullStr | Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus |
| title_full_unstemmed | Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus |
| title_short | Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus |
| title_sort | automated quantitative analysis of saccadic characteristics in patients with spontaneous and head shaking nystagmus |
| topic | spontaneous nystagmus head-shaking nystagmus saccadic wave vestibular function assessment video head impulse test |
| url | https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.10.010 |
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