The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review

ABSTRACT Purpose This scoping review aims to explore the relationship between health‐promoting lifestyle behaviors and gut microbiota in survivors of hematological cancers, including leukemia, lymphoma, and multiple myeloma. Given the rising incidence of these malignancies and the associated treatme...

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Main Authors: Elham Samami, Angela Starkweather, Debra Lynch Kelly, Debra Lyon
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Cancer Reports
Subjects:
Online Access:https://doi.org/10.1002/cnr2.70224
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author Elham Samami
Angela Starkweather
Debra Lynch Kelly
Debra Lyon
author_facet Elham Samami
Angela Starkweather
Debra Lynch Kelly
Debra Lyon
author_sort Elham Samami
collection DOAJ
description ABSTRACT Purpose This scoping review aims to explore the relationship between health‐promoting lifestyle behaviors and gut microbiota in survivors of hematological cancers, including leukemia, lymphoma, and multiple myeloma. Given the rising incidence of these malignancies and the associated treatment challenges, understanding how lifestyle factors influence gut health may provide insights into improving survivorship outcomes. Methods We conducted a comprehensive search across multiple databases, including PubMed/Medline, CINAHL, and Scopus, following the Preferred Reporting Items for Systematic Reviews and Meta‐Analysis extension for Scoping Reviews (PRISMA‐ScR). The search strategy incorporated MeSH terms related to hematological cancers, health‐promoting lifestyle behaviors, and gut microbiota. Inclusion criteria focused on primary research studies published in English that reported gut microbiota results in survivors of hematological cancers. A total of 1717 papers were initially identified, with 16 studies meeting the inclusion criteria after screening for relevance. Results The review identified a significant association between health‐promoting lifestyle behaviors, such as physical activity, nutrition, and stress management, and the composition and diversity of gut microbiota in cancer survivors. The findings suggest that engaging in these behaviors may enhance gut health, potentially mitigating treatment‐related symptoms and improving overall quality of life. Notably, the studies highlighted the importance of tailored interventions that consider individual patient needs and preferences. Conclusions This scoping review underscores the critical role of health‐promoting lifestyle behaviors in influencing gut microbiota among survivors of hematological cancers. Future research should focus on longitudinal studies to establish causal relationships and explore the mechanisms underlying these associations. By promoting healthy lifestyle choices, healthcare providers can enhance survivorship care and improve health outcomes for this population.
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spelling doaj-art-1da972291d084cdabfc9e642014464272025-08-20T02:30:23ZengWileyCancer Reports2573-83482025-05-0185n/an/a10.1002/cnr2.70224The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping ReviewElham Samami0Angela Starkweather1Debra Lynch Kelly2Debra Lyon3College of Nursing University of Florida, Health Cancer Center Gainesville Florida USACollege of Nursing Rutgers University Newark New Jersey USALoewenberg College of Nursing University of Memphis Memphis Tennessee USACollege of Nursing University of Florida, Health Cancer Center Gainesville Florida USAABSTRACT Purpose This scoping review aims to explore the relationship between health‐promoting lifestyle behaviors and gut microbiota in survivors of hematological cancers, including leukemia, lymphoma, and multiple myeloma. Given the rising incidence of these malignancies and the associated treatment challenges, understanding how lifestyle factors influence gut health may provide insights into improving survivorship outcomes. Methods We conducted a comprehensive search across multiple databases, including PubMed/Medline, CINAHL, and Scopus, following the Preferred Reporting Items for Systematic Reviews and Meta‐Analysis extension for Scoping Reviews (PRISMA‐ScR). The search strategy incorporated MeSH terms related to hematological cancers, health‐promoting lifestyle behaviors, and gut microbiota. Inclusion criteria focused on primary research studies published in English that reported gut microbiota results in survivors of hematological cancers. A total of 1717 papers were initially identified, with 16 studies meeting the inclusion criteria after screening for relevance. Results The review identified a significant association between health‐promoting lifestyle behaviors, such as physical activity, nutrition, and stress management, and the composition and diversity of gut microbiota in cancer survivors. The findings suggest that engaging in these behaviors may enhance gut health, potentially mitigating treatment‐related symptoms and improving overall quality of life. Notably, the studies highlighted the importance of tailored interventions that consider individual patient needs and preferences. Conclusions This scoping review underscores the critical role of health‐promoting lifestyle behaviors in influencing gut microbiota among survivors of hematological cancers. Future research should focus on longitudinal studies to establish causal relationships and explore the mechanisms underlying these associations. By promoting healthy lifestyle choices, healthcare providers can enhance survivorship care and improve health outcomes for this population.https://doi.org/10.1002/cnr2.70224gut microbiotahealth‐promoting lifestyle behaviorshematological cancernutritionsurvivorship
spellingShingle Elham Samami
Angela Starkweather
Debra Lynch Kelly
Debra Lyon
The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review
Cancer Reports
gut microbiota
health‐promoting lifestyle behaviors
hematological cancer
nutrition
survivorship
title The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review
title_full The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review
title_fullStr The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review
title_full_unstemmed The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review
title_short The Impact of Health‐Promoting Lifestyle Behaviors on Gut Microbiota in Survivors of Hematological Cancer: A Scoping Review
title_sort impact of health promoting lifestyle behaviors on gut microbiota in survivors of hematological cancer a scoping review
topic gut microbiota
health‐promoting lifestyle behaviors
hematological cancer
nutrition
survivorship
url https://doi.org/10.1002/cnr2.70224
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