Impact of maintenance hemodialysis on cognitive function of patients
Objective To investigate the impact of maintenance hemodialysis(MHD) on cognitive function of patients with chronic renal failure(CRF).Methods Sixty-five cases of CRF undergoing MHD were recruited between January 2014 to August 2015 from Department of Nephrology,the People’s Hospital of Boertala Zho...
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| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2016-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57918539&Fpath=home&index=0 |
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| Summary: | Objective To investigate the impact of maintenance hemodialysis(MHD) on cognitive function of patients with chronic renal failure(CRF).Methods Sixty-five cases of CRF undergoing MHD were recruited between January 2014 to August 2015 from Department of Nephrology,the People’s Hospital of Boertala Zhou.The effect of MDH on cognitive function in patients with CRF was observed.The cognitive function was assessed by the Montreal Cognitive Scale(MoCA) before and after treatment Sixty-five patients were divided into normal cognition(NC) group(n = 22),and cognitive impairment(CD group(n = 43) according to the MoCA scores.Results The average scores of MoCA in MHD patients were(21.8 ± 4.4),which were significantly lower than those in the control group.After MHD,the MoCA scores in NC group(23.2 ± 1.7) and CI group(18.7 ± 3.6) were significantly lower than those before MHD[(26.5 ± 1.2) and(21.3 ± 2.9) respectively].There was significant difference between the two groups(P<0.05).The multivariate analysis revealed that low education level,older age,low hemoglobin levels and a long duration of dialysis were factors influencing cognitive dysfunction of MHD patients with the differences being statistically significant(P<0.05).Conclusions MHD can influence cognitive function in patients with CRF,and education level,age,hemoglobin levels and duration of dialysis may be the risk factors. |
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| ISSN: | 1671-2390 |