Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab world

Neuropsychiatric symptoms in Parkinson’s disease (PD) are common, underrecognized, and impact patients’ quality of life. Research around this topic is scarce in the Arab world. The aim of this comprehensive narrative review was to examine available evidence and discusses its strengths and limitation...

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Main Authors: Alfred Chabbouh, Hassan Khalil, Chafic Abboud, Antoine Sader, Rita Khoury
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605241304646
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author Alfred Chabbouh
Hassan Khalil
Chafic Abboud
Antoine Sader
Rita Khoury
author_facet Alfred Chabbouh
Hassan Khalil
Chafic Abboud
Antoine Sader
Rita Khoury
author_sort Alfred Chabbouh
collection DOAJ
description Neuropsychiatric symptoms in Parkinson’s disease (PD) are common, underrecognized, and impact patients’ quality of life. Research around this topic is scarce in the Arab world. The aim of this comprehensive narrative review was to examine available evidence and discusses its strengths and limitations. The PubMed and Embase databases were searched using relevant keywords for studies published between 2000 and 2023. A total of 10 epidemiological and three assessment tool validation studies of neuropsychiatric symptoms in PD, conducted in the 22 Arab countries, were included. Only four Arab countries contributed to the 10 epidemiological studies found. Egypt provided the largest number of patients. Prevalence rates of neuropsychiatric symptoms in PD were heterogenous. Three studies relied on the Non-Motor Symptom Scale to estimate prevalence. Three studies used validated screening tools for dementia. Five studies used specific screening tools for depression, while two used the Diagnostic and Statistical Manual of mental disorders, fourth edition (DSM-IV) diagnostic criteria for depression. No appropriate and validated tool is available to assess for apathy. The generalizability of the findings is limited and recommendations for future studies are provided.
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spelling doaj-art-1d9f4c6424a941d696a7b7bb6cc087dc2025-08-20T02:49:36ZengSAGE PublishingJournal of International Medical Research1473-23002024-12-015210.1177/03000605241304646Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab worldAlfred ChabbouhHassan KhalilChafic AbboudAntoine SaderRita KhouryNeuropsychiatric symptoms in Parkinson’s disease (PD) are common, underrecognized, and impact patients’ quality of life. Research around this topic is scarce in the Arab world. The aim of this comprehensive narrative review was to examine available evidence and discusses its strengths and limitations. The PubMed and Embase databases were searched using relevant keywords for studies published between 2000 and 2023. A total of 10 epidemiological and three assessment tool validation studies of neuropsychiatric symptoms in PD, conducted in the 22 Arab countries, were included. Only four Arab countries contributed to the 10 epidemiological studies found. Egypt provided the largest number of patients. Prevalence rates of neuropsychiatric symptoms in PD were heterogenous. Three studies relied on the Non-Motor Symptom Scale to estimate prevalence. Three studies used validated screening tools for dementia. Five studies used specific screening tools for depression, while two used the Diagnostic and Statistical Manual of mental disorders, fourth edition (DSM-IV) diagnostic criteria for depression. No appropriate and validated tool is available to assess for apathy. The generalizability of the findings is limited and recommendations for future studies are provided.https://doi.org/10.1177/03000605241304646
spellingShingle Alfred Chabbouh
Hassan Khalil
Chafic Abboud
Antoine Sader
Rita Khoury
Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab world
Journal of International Medical Research
title Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab world
title_full Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab world
title_fullStr Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab world
title_full_unstemmed Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab world
title_short Neuropsychiatric symptoms in Parkinson’s disease: review of data from the Arab world
title_sort neuropsychiatric symptoms in parkinson s disease review of data from the arab world
url https://doi.org/10.1177/03000605241304646
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