Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report
Abstract Background Erythropoietic protoporphyria (EPP) is a rare disorder of heme synthesis. Patients with EPP mainly show symptoms of photosensitivity, but approximately 20% of EPPs are associated with the liver-related complications. We report a case of breast cancer in a 48-year-old female patie...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Japan Surgical Society
2021-01-01
|
| Series: | Surgical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40792-020-01068-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850092819407962112 |
|---|---|
| author | Akiko Shimazaki Takuma Hashimoto Masaya Kai Tetsuzo Nakayama Mai Yamada Karen Zaguirre Kentaro Tokuda Makoto Kubo Ken Yamaura Masafumi Nakamura |
| author_facet | Akiko Shimazaki Takuma Hashimoto Masaya Kai Tetsuzo Nakayama Mai Yamada Karen Zaguirre Kentaro Tokuda Makoto Kubo Ken Yamaura Masafumi Nakamura |
| author_sort | Akiko Shimazaki |
| collection | DOAJ |
| description | Abstract Background Erythropoietic protoporphyria (EPP) is a rare disorder of heme synthesis. Patients with EPP mainly show symptoms of photosensitivity, but approximately 20% of EPPs are associated with the liver-related complications. We report a case of breast cancer in a 48-year-old female patient with EPP in whom meticulous perioperative management was required in order to avoid complications resulting from this disease. Case presentation The patient was diagnosed with EPP at the age of 33 and had a rich family history of the disease. For right breast cancer initially considered as TisN0M0 (Stage 0), the right mastectomy and sentinel lymph node biopsy were performed, while the final stage was pT1bN0M0, pStage I. In the perioperative period, we limited the drug use and monitored light wavelength measurements. Besides, we covered surgical lights, headlights, and laryngoscope’s light with a special polyimide film that filtered the wavelength of light causing dermal photosensitivity. After the surgery, any emerging complications were closely monitored. Conclusions The surgery, internal medicine, anesthesiology, and operation departments undertook all possible measures through close cooperation to ensure a safe surgery for the patient with a rare condition. |
| format | Article |
| id | doaj-art-1d86ff955d414e2989ec2f172d1f548b |
| institution | DOAJ |
| issn | 2198-7793 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-1d86ff955d414e2989ec2f172d1f548b2025-08-20T02:42:03ZengJapan Surgical SocietySurgical Case Reports2198-77932021-01-01711610.1186/s40792-020-01068-5Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case reportAkiko Shimazaki0Takuma Hashimoto1Masaya Kai2Tetsuzo Nakayama3Mai Yamada4Karen Zaguirre5Kentaro Tokuda6Makoto Kubo7Ken Yamaura8Masafumi Nakamura9Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Anesthesiology and Critical Care Medicine, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu UniversityOperating Room, Kyushu University HospitalDepartment of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu UniversityEmergency and Critical Care Center, Kyushu University HospitalDepartment of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Anesthesiology and Critical Care Medicine, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu UniversityAbstract Background Erythropoietic protoporphyria (EPP) is a rare disorder of heme synthesis. Patients with EPP mainly show symptoms of photosensitivity, but approximately 20% of EPPs are associated with the liver-related complications. We report a case of breast cancer in a 48-year-old female patient with EPP in whom meticulous perioperative management was required in order to avoid complications resulting from this disease. Case presentation The patient was diagnosed with EPP at the age of 33 and had a rich family history of the disease. For right breast cancer initially considered as TisN0M0 (Stage 0), the right mastectomy and sentinel lymph node biopsy were performed, while the final stage was pT1bN0M0, pStage I. In the perioperative period, we limited the drug use and monitored light wavelength measurements. Besides, we covered surgical lights, headlights, and laryngoscope’s light with a special polyimide film that filtered the wavelength of light causing dermal photosensitivity. After the surgery, any emerging complications were closely monitored. Conclusions The surgery, internal medicine, anesthesiology, and operation departments undertook all possible measures through close cooperation to ensure a safe surgery for the patient with a rare condition.https://doi.org/10.1186/s40792-020-01068-5Erythropoietic protoporphyria (EPP)PhotosensitivityBreast cancer surgery |
| spellingShingle | Akiko Shimazaki Takuma Hashimoto Masaya Kai Tetsuzo Nakayama Mai Yamada Karen Zaguirre Kentaro Tokuda Makoto Kubo Ken Yamaura Masafumi Nakamura Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report Surgical Case Reports Erythropoietic protoporphyria (EPP) Photosensitivity Breast cancer surgery |
| title | Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report |
| title_full | Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report |
| title_fullStr | Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report |
| title_full_unstemmed | Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report |
| title_short | Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report |
| title_sort | surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity a case report |
| topic | Erythropoietic protoporphyria (EPP) Photosensitivity Breast cancer surgery |
| url | https://doi.org/10.1186/s40792-020-01068-5 |
| work_keys_str_mv | AT akikoshimazaki surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT takumahashimoto surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT masayakai surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT tetsuzonakayama surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT maiyamada surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT karenzaguirre surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT kentarotokuda surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT makotokubo surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT kenyamaura surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport AT masafuminakamura surgicaltreatmentforbreastcancerinapatientwitherythropoieticprotoporphyriaandphotosensitivityacasereport |