Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a Review
INTRODUCTION. Drinking of natural medicinal mineral waters is the basis of spa treatment for patients with digestive diseases and metabolic disorders. AIM. To search for and analyze the results of scientific studies devoted to studying the mechanisms of action of drinking mineral waters of the Es...
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Ministry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and Balneology
2025-01-01
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| Series: | Вестник восстановительной медицины |
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| author | Tatiana V. Konchugova Tatiana V. Apkhanova Tatyana V. Marfina Detelina B. Kulchitskaya Larisa A. Marchenkova Valeriia A. Vasileva Maxim Yu. Yakovlev Olga M. Musaeva |
| author_facet | Tatiana V. Konchugova Tatiana V. Apkhanova Tatyana V. Marfina Detelina B. Kulchitskaya Larisa A. Marchenkova Valeriia A. Vasileva Maxim Yu. Yakovlev Olga M. Musaeva |
| author_sort | Tatiana V. Konchugova |
| collection | DOAJ |
| description | INTRODUCTION. Drinking of natural medicinal mineral waters is the basis of spa treatment for patients with digestive diseases and metabolic disorders.
AIM. To search for and analyze the results of scientific studies devoted to studying the mechanisms of action of drinking mineral waters of the Essentuki group, as well as the effectiveness of using “Essentuki-4”, “Essentuki-17”, “Narzan” mineral waters in various gastroenterological diseases, metabolic diseases and urinary system.
MATERIALS AND METHODS. A search was conducted in the scientific databases of the eLIBRАRY.RU, Scopus, PubMed for scientific publications, including literature reviews, results of RCTs, comparative studies, as well as published patents, methodological manuals, guidelines for doctors, monographs devoted to the effectiveness of the use of the Essentuki group of mineral waters and Narzan mineral waters in various gastroenterological diseases, diseases of the urinary system and metabolism for the period from 1972 to September 2024. A total of 103 publications were selected, including 81 articles in domestic peer-reviewed scientific journals, 4 national guidelines, 6 patents of the Russian Federation, 6 manuals for doctors, 6 monographs by leading domestic balneologists.
RESULTS AND DISCUSSION. Scientific analysis of experimental and clinical studies conducted by scientists from the Pyatigorsk Research Institute of Balneology showed that the multifaceted therapeutic effect of drinking mineral waters of the Essentuki type is realized not only due to the unique physical and chemical composition, but also due to the increase in the level of functional reserves of the body. Thus, under the influence of a single and course intake of mineral waters, an increase in the secretion of most digestive hormones (gastrin, glucagon, insulin, cholecystokinin, vasoactive intestinal polypeptide, etc.) was revealed, activating trophic processes in the digestive organs. The established mechanism of action of drinking mineral waters is also associated with their influence on endocrine cells of the intestinal hormonal system, with the adaptive restructuring of the activity of hormonal systems of higher levels of biological integration, where the activation of the early phase of insulin and serotonin secretion is decisive. Also, scientists from the Pyatigorsk Research Institute of Balneology formulated a theory considering the intake of drinking mineral waters as a short-stress stimulating factor that activates adaptive sanogenetic gastrointestinal hormonal mechanisms that are realized through increasing the tension of the antioxidant and insulin-regulating systems.
CONCLUSION. The analysis of the conducted randomized scientific studies revealed that drinking mineral waters of the Essentuki type and Narzan in complex spa treatment allows modifying physiological, metabolic processes, has a preventive effect, improves the results of treatment of the main gastroenterological diseases and metabolic diseases, improves the quality of life of patients and prevents the progression of diseases, affecting the correction of the main risk factors (obesity, hyperlipidemia, hyperglycemia, physical inactivity). |
| format | Article |
| id | doaj-art-1d819e77a4e3443591933ad4baa65ac2 |
| institution | OA Journals |
| issn | 2078-1962 2713-2625 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Ministry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and Balneology |
| record_format | Article |
| series | Вестник восстановительной медицины |
| spelling | doaj-art-1d819e77a4e3443591933ad4baa65ac22025-08-20T02:09:14ZengMinistry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and BalneologyВестник восстановительной медицины2078-19622713-26252025-01-01242567010.38025/2078-1962-2025-24-2-56-701471Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a ReviewTatiana V. Konchugova0https://orcid.org/0000-0003-0991-8988Tatiana V. Apkhanova1https://orcid.org/0000-0003-3852-2050Tatyana V. Marfina2https://orcid.org/0000-0002-2553-1946Detelina B. Kulchitskaya3https://orcid.org/0000-0002-7785-9767Larisa A. Marchenkova4https://orcid.org/0000-0003-1886-124XValeriia A. Vasileva5https://orcid.org/0000-0002-6526-4512Maxim Yu. Yakovlev6https://orcid.org/0000-0002-5260-8304Olga M. Musaeva7https://orcid.org/0000-0001-9146-0966National Medical Research Center for Rehabilitation and BalneologyNational Medical Research Center for Rehabilitation and BalneologyNational Medical Research Center for Rehabilitation and BalneologyNational Medical Research Center for Rehabilitation and BalneologyNational Medical Research Center for Rehabilitation and BalneologyNational Medical Research Center for Rehabilitation and BalneologyNational Medical Research Center for Rehabilitation and BalneologyNational Medical Research Center for Rehabilitation and BalneologyINTRODUCTION. Drinking of natural medicinal mineral waters is the basis of spa treatment for patients with digestive diseases and metabolic disorders. AIM. To search for and analyze the results of scientific studies devoted to studying the mechanisms of action of drinking mineral waters of the Essentuki group, as well as the effectiveness of using “Essentuki-4”, “Essentuki-17”, “Narzan” mineral waters in various gastroenterological diseases, metabolic diseases and urinary system. MATERIALS AND METHODS. A search was conducted in the scientific databases of the eLIBRАRY.RU, Scopus, PubMed for scientific publications, including literature reviews, results of RCTs, comparative studies, as well as published patents, methodological manuals, guidelines for doctors, monographs devoted to the effectiveness of the use of the Essentuki group of mineral waters and Narzan mineral waters in various gastroenterological diseases, diseases of the urinary system and metabolism for the period from 1972 to September 2024. A total of 103 publications were selected, including 81 articles in domestic peer-reviewed scientific journals, 4 national guidelines, 6 patents of the Russian Federation, 6 manuals for doctors, 6 monographs by leading domestic balneologists. RESULTS AND DISCUSSION. Scientific analysis of experimental and clinical studies conducted by scientists from the Pyatigorsk Research Institute of Balneology showed that the multifaceted therapeutic effect of drinking mineral waters of the Essentuki type is realized not only due to the unique physical and chemical composition, but also due to the increase in the level of functional reserves of the body. Thus, under the influence of a single and course intake of mineral waters, an increase in the secretion of most digestive hormones (gastrin, glucagon, insulin, cholecystokinin, vasoactive intestinal polypeptide, etc.) was revealed, activating trophic processes in the digestive organs. The established mechanism of action of drinking mineral waters is also associated with their influence on endocrine cells of the intestinal hormonal system, with the adaptive restructuring of the activity of hormonal systems of higher levels of biological integration, where the activation of the early phase of insulin and serotonin secretion is decisive. Also, scientists from the Pyatigorsk Research Institute of Balneology formulated a theory considering the intake of drinking mineral waters as a short-stress stimulating factor that activates adaptive sanogenetic gastrointestinal hormonal mechanisms that are realized through increasing the tension of the antioxidant and insulin-regulating systems. CONCLUSION. The analysis of the conducted randomized scientific studies revealed that drinking mineral waters of the Essentuki type and Narzan in complex spa treatment allows modifying physiological, metabolic processes, has a preventive effect, improves the results of treatment of the main gastroenterological diseases and metabolic diseases, improves the quality of life of patients and prevents the progression of diseases, affecting the correction of the main risk factors (obesity, hyperlipidemia, hyperglycemia, physical inactivity).https://journals.eco-vector.com/2078-1962/article/viewFile/653414/194037mineral wateressentuki-4essentuki-17narzangastroenterological diseasesmetabolic disordersmetabolic syndrome |
| spellingShingle | Tatiana V. Konchugova Tatiana V. Apkhanova Tatyana V. Marfina Detelina B. Kulchitskaya Larisa A. Marchenkova Valeriia A. Vasileva Maxim Yu. Yakovlev Olga M. Musaeva Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a Review Вестник восстановительной медицины mineral water essentuki-4 essentuki-17 narzan gastroenterological diseases metabolic disorders metabolic syndrome |
| title | Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a Review |
| title_full | Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a Review |
| title_fullStr | Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a Review |
| title_full_unstemmed | Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a Review |
| title_short | Efficiency of Therapeutic Use and Mechanisms of Therapeutic Effect of "Essentuki" and "Narzan" Mineral Waters in Various Diseases: a Review |
| title_sort | efficiency of therapeutic use and mechanisms of therapeutic effect of essentuki and narzan mineral waters in various diseases a review |
| topic | mineral water essentuki-4 essentuki-17 narzan gastroenterological diseases metabolic disorders metabolic syndrome |
| url | https://journals.eco-vector.com/2078-1962/article/viewFile/653414/194037 |
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