Connective tissue dysplasia syndrome in nephrology. Literature review
Background. Connective tissue dysplasia is a heterogeneous group of conditions that, in turn, can lead to the formation of pathology of various organs, accompanied by violations of their morphology and function, which reduces the quality of life of patients, contributes to the unfavorable course and...
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Open Systems Publication
2024-01-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/1178 |
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| author | R. A. Zorina I. V. Zorin |
| author_facet | R. A. Zorina I. V. Zorin |
| author_sort | R. A. Zorina |
| collection | DOAJ |
| description | Background. Connective tissue dysplasia is a heterogeneous group of conditions that, in turn, can lead to the formation of pathology of various organs, accompanied by violations of their morphology and function, which reduces the quality of life of patients, contributes to the unfavorable course and outcome of diseases occurring against the background of connective tissue dysplasia, and sometimes even disability. Phenotypic manifestations of connective tissue dysplasia are quite diverse. The structural features of connective tissue affect the development and course of pathology of the urinary system. Currently, mutations in collagen genes leading to the development of kidney diseases have been established, and the relationship between the severity of connective tissue dysplasia and the development of abnormalities of the urinary system organs has been proven, antenatal risk factors for the formation of congenital malformations of the urinary system organs against the background of connective tissue dysplasia and children have been identified.Objective. The purpose of the study was to evaluate the role of connective tissue dysplasia syndrome on the development and course of pathology of the urinary system organs.Materials and methods: the analysis of 24 sources of scientific literature on the topic under study, connective tissue dysplasia syndrome in nephrology.Results. The analysis of scientific literature data was carried out. Modern data on the effect of connective tissue dysplasia syndrome on the development and course of pathology of the urinary system organs in children are presented. The features of the course are presented and the degree of influence of connective tissue dysplasia on the pathology of the urinary system is described.Conclusion. Connective tissue dysplasia syndrome is the basis for the development of pathology of the urinary system in children. Therefore, connective tissue dysplasia requires a targeted search for criteria for identifying patients at risk for kidney damage. |
| format | Article |
| id | doaj-art-1d79efd041404ffba65e4dfef1627e62 |
| institution | Kabale University |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2024-01-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-1d79efd041404ffba65e4dfef1627e622025-08-20T03:37:06ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812024-01-0101374110.51793/OS.2024.27.1.0051167Connective tissue dysplasia syndrome in nephrology. Literature reviewR. A. Zorina0I. V. Zorin1Federal State Budgetary Educational Institution of Higher Education Orenburg State Medical University of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education Orenburg State Medical University of the Ministry of Health of the Russian FederationBackground. Connective tissue dysplasia is a heterogeneous group of conditions that, in turn, can lead to the formation of pathology of various organs, accompanied by violations of their morphology and function, which reduces the quality of life of patients, contributes to the unfavorable course and outcome of diseases occurring against the background of connective tissue dysplasia, and sometimes even disability. Phenotypic manifestations of connective tissue dysplasia are quite diverse. The structural features of connective tissue affect the development and course of pathology of the urinary system. Currently, mutations in collagen genes leading to the development of kidney diseases have been established, and the relationship between the severity of connective tissue dysplasia and the development of abnormalities of the urinary system organs has been proven, antenatal risk factors for the formation of congenital malformations of the urinary system organs against the background of connective tissue dysplasia and children have been identified.Objective. The purpose of the study was to evaluate the role of connective tissue dysplasia syndrome on the development and course of pathology of the urinary system organs.Materials and methods: the analysis of 24 sources of scientific literature on the topic under study, connective tissue dysplasia syndrome in nephrology.Results. The analysis of scientific literature data was carried out. Modern data on the effect of connective tissue dysplasia syndrome on the development and course of pathology of the urinary system organs in children are presented. The features of the course are presented and the degree of influence of connective tissue dysplasia on the pathology of the urinary system is described.Conclusion. Connective tissue dysplasia syndrome is the basis for the development of pathology of the urinary system in children. Therefore, connective tissue dysplasia requires a targeted search for criteria for identifying patients at risk for kidney damage.https://journal.lvrach.ru/jour/article/view/1178connective tissue dysplasiaphenotypic and visceral manifestationspathology of the urinary system |
| spellingShingle | R. A. Zorina I. V. Zorin Connective tissue dysplasia syndrome in nephrology. Literature review Лечащий Врач connective tissue dysplasia phenotypic and visceral manifestations pathology of the urinary system |
| title | Connective tissue dysplasia syndrome in nephrology. Literature review |
| title_full | Connective tissue dysplasia syndrome in nephrology. Literature review |
| title_fullStr | Connective tissue dysplasia syndrome in nephrology. Literature review |
| title_full_unstemmed | Connective tissue dysplasia syndrome in nephrology. Literature review |
| title_short | Connective tissue dysplasia syndrome in nephrology. Literature review |
| title_sort | connective tissue dysplasia syndrome in nephrology literature review |
| topic | connective tissue dysplasia phenotypic and visceral manifestations pathology of the urinary system |
| url | https://journal.lvrach.ru/jour/article/view/1178 |
| work_keys_str_mv | AT razorina connectivetissuedysplasiasyndromeinnephrologyliteraturereview AT ivzorin connectivetissuedysplasiasyndromeinnephrologyliteraturereview |