The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and Isoborneol

Protection of the hydroxy group in monoterpenoids borneol and isoborneol with various silyl-protective groups containing a different number of phenyl groups enabled complete assignments of the <sup>1</sup>H chemical shifts. In particular, a wider range of the protons in isoborneol and it...

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Main Authors: Baohe Lyu, Mio Sugiura, Koya Tayama, Yoshikazu Hiraga, Ryukichi Takagi, Satomi Niwayama
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Molbank
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Online Access:https://www.mdpi.com/1422-8599/2024/4/M1908
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author Baohe Lyu
Mio Sugiura
Koya Tayama
Yoshikazu Hiraga
Ryukichi Takagi
Satomi Niwayama
author_facet Baohe Lyu
Mio Sugiura
Koya Tayama
Yoshikazu Hiraga
Ryukichi Takagi
Satomi Niwayama
author_sort Baohe Lyu
collection DOAJ
description Protection of the hydroxy group in monoterpenoids borneol and isoborneol with various silyl-protective groups containing a different number of phenyl groups enabled complete assignments of the <sup>1</sup>H chemical shifts. In particular, a wider range of the protons in isoborneol and its silyl-protected derivatives were influenced than those in borneol and its silyl-protected derivatives, which is likely to be due to the anisotropic effects from the phenyl groups. Understanding these effects allows for the interpretation of the <sup>1</sup>H NMR spectra and provides information about how silyl-protecting groups affect these spectra.
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spelling doaj-art-1d791e92ccfa4504a9c4f56d6adfd4b92025-08-20T02:43:20ZengMDPI AGMolbank1422-85992024-10-0120244M190810.3390/M1908The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and IsoborneolBaohe Lyu0Mio Sugiura1Koya Tayama2Yoshikazu Hiraga3Ryukichi Takagi4Satomi Niwayama5Graduate School of Science and Technology, Hiroshima Institute of Technology, Hiroshima 731-5193, JapanGraduate School of Science and Technology, Hiroshima Institute of Technology, Hiroshima 731-5193, JapanGraduate School of Science and Technology, Hiroshima Institute of Technology, Hiroshima 731-5193, JapanGraduate School of Science and Technology, Hiroshima Institute of Technology, Hiroshima 731-5193, JapanDepartment of Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, Higashi-Hiroshima 739-8526, JapanGraduate School of Engineering, Muroran Institute of Technology, Muroran 050-8585, JapanProtection of the hydroxy group in monoterpenoids borneol and isoborneol with various silyl-protective groups containing a different number of phenyl groups enabled complete assignments of the <sup>1</sup>H chemical shifts. In particular, a wider range of the protons in isoborneol and its silyl-protected derivatives were influenced than those in borneol and its silyl-protected derivatives, which is likely to be due to the anisotropic effects from the phenyl groups. Understanding these effects allows for the interpretation of the <sup>1</sup>H NMR spectra and provides information about how silyl-protecting groups affect these spectra.https://www.mdpi.com/1422-8599/2024/4/M1908NMR assignmentchemical shift changeanisotropic effectsilyl-protective group
spellingShingle Baohe Lyu
Mio Sugiura
Koya Tayama
Yoshikazu Hiraga
Ryukichi Takagi
Satomi Niwayama
The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and Isoborneol
Molbank
NMR assignment
chemical shift change
anisotropic effect
silyl-protective group
title The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and Isoborneol
title_full The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and Isoborneol
title_fullStr The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and Isoborneol
title_full_unstemmed The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and Isoborneol
title_short The Shielding Effect of Phenyl Groups in the Silyl-Protecting Groups Introduced into Borneol and Isoborneol
title_sort shielding effect of phenyl groups in the silyl protecting groups introduced into borneol and isoborneol
topic NMR assignment
chemical shift change
anisotropic effect
silyl-protective group
url https://www.mdpi.com/1422-8599/2024/4/M1908
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