Quantitative PCR for parasitemia monitoring and preemptive therapy in patients with Chagas disease and autoimmune rheumatic disorders undergoing biologic treatment: a case series

Quantitative PCR for parasitemia monitoring and preemptive therapy in patients with Chagas disease and autoimmune rheumatic disorders undergoing biologic treatment: a case series

ABSTRACT Patients with chronic Chagas disease (CD) and autoimmune rheumatic disorders (ARD) receiving immunosuppressive therapy are at risk for CD reactivation (CDR). This study monitored parasitemia over 9-121 months in six patients with CD and ARD using conventional and quantitative PCR and parasi...

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Main Authors: Noemia Barbosa Carvalho, Vera Lucia Teixeira de Freitas, Nadia Emi Aikawa, Lucas Teixeira Vieira, Rita Cristina Bezerra, Adriana Coraccini Tonácio de Proença, Karina Bonfiglioli, Érika Yoshie Shimoda Nakanishi, Hermes Ryoiti Higashino, Maria Aparecida Shikanai-Yasuda
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2025-06-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Chagas disease
Autoimmune rheumatic diseases
T. cruzi
Parasitemia
qPCR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822025000100802&lng=en&tlng=en
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