Ketamine and melatonin for the prevention of postoperative delirium in patients with colorectal cancer: a feasibility study

Ketamine and melatonin for the prevention of postoperative delirium in patients with colorectal cancer: a feasibility study

Abstract Purpose This study aimed to examine the feasibility and effects of preoperative 5 mg of melatonin and intraoperative 50 mg of ketamine on postoperative delirium (POD) prevention in candidates for colorectal cancer surgery. Methods In this randomized controlled trial, adults (> 18 years)...

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Bibliographic Details
Main Authors: Kousha Farhadi, Mojgan Rahimi, Hesam Varpaei, Erta Rajabi, Seyyed Mohammad Mahdi Tayebi Tafreshi, Parsa Mohammadi, Mostafa Mohammadi
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Perioperative Medicine
Subjects:
Delirium
Melatonin
Ketamine
Anesthesia
Colorectal neoplasms
Online Access:https://doi.org/10.1186/s13741-025-00571-3
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