Distinct prognostic implications of blood neuronal and astroglial biomarkers in neuromyelitis optica spectrum disorders versus multiple sclerosis

Distinct prognostic implications of blood neuronal and astroglial biomarkers in neuromyelitis optica spectrum disorders versus multiple sclerosis

Abstract Research on neuronal and astroglial markers for predicting outcomes in aquaporin-4 antibody-seropositive neuromyelitis optica spectrum disorders (NMOSD) remains limited. We aimed to evaluate the prognostic value of blood biomarkers for neuronal and astroglial damage in NMOSD compared with m...

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Main Authors: Wangyong Shin, Eun-Jae Lee, Dayoung Seo, Bum Joon Choi, Inhye Jang, Jin Hee Kim, Lynkyung Choi, Keonwoo Kim, Ji-Yon Kim, Hee-Jae Jung, Hyemi Lee, Hyunjin Kim, Young-Min Lim
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Neuromyelitis Optica spectrum disorder
Multiple sclerosis
Biomarkers
Neurofilament light
Glial fibrillary acidic protein
Online Access:https://doi.org/10.1038/s41598-025-95773-6
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