A case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.nov
Abstract Background Ottowia massiliensis sp.nov. is a slow-growing and Gram-stain-negative bacillus, first isolated from the stool sample of a healthy volunteer. Due to its slow growth and challenging cultivation, it is easily overlooked in clinical microbiology laboratories. This case report is the...
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BMC
2025-04-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-025-04007-w |
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| author | Yuxuan Wu Hua Sun Min Kang Kexin Chen Qingfeng Liang Xinxin Lu |
| author_facet | Yuxuan Wu Hua Sun Min Kang Kexin Chen Qingfeng Liang Xinxin Lu |
| author_sort | Yuxuan Wu |
| collection | DOAJ |
| description | Abstract Background Ottowia massiliensis sp.nov. is a slow-growing and Gram-stain-negative bacillus, first isolated from the stool sample of a healthy volunteer. Due to its slow growth and challenging cultivation, it is easily overlooked in clinical microbiology laboratories. This case report is the first case of its pathogenicity. Case presentation This case report describes a case of canaliculitis caused by Ottowia massiliensis sp.nov. The patient, an 80-year-old woman, presented with bilateral epiphora and discharge lasting for 4 years, which worsened with redness and swelling over the past week. Microbial culture of the lacrimal duct secretion after 72 h on Columbia blood agar showed small colonies. MALDI-TOF MS did not yield accurate results, but 16 S rDNA sequencing identified the bacterium as Ottowia massiliensis sp.nov. (LT960589.1). Antimicrobial sensitivity tests showed high activity against most ophthalmic drugs. Conclusions In the case described here, we discuss the diagnosis and treatment strategies for eye infections caused by Ottowia massiliensis sp.nov., laying the foundation for improving clinical and laboratory awareness of this bacterium. |
| format | Article |
| id | doaj-art-1d64380754d643b79f9cfff09c675ce6 |
| institution | OA Journals |
| issn | 1471-2415 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj-art-1d64380754d643b79f9cfff09c675ce62025-08-20T02:17:50ZengBMCBMC Ophthalmology1471-24152025-04-012511310.1186/s12886-025-04007-wA case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.novYuxuan Wu0Hua Sun1Min Kang2Kexin Chen3Qingfeng Liang4Xinxin Lu5Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical UniversityBeijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical UniversityBeijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical UniversityBeijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical UniversityBeijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical UniversityBeijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical UniversityAbstract Background Ottowia massiliensis sp.nov. is a slow-growing and Gram-stain-negative bacillus, first isolated from the stool sample of a healthy volunteer. Due to its slow growth and challenging cultivation, it is easily overlooked in clinical microbiology laboratories. This case report is the first case of its pathogenicity. Case presentation This case report describes a case of canaliculitis caused by Ottowia massiliensis sp.nov. The patient, an 80-year-old woman, presented with bilateral epiphora and discharge lasting for 4 years, which worsened with redness and swelling over the past week. Microbial culture of the lacrimal duct secretion after 72 h on Columbia blood agar showed small colonies. MALDI-TOF MS did not yield accurate results, but 16 S rDNA sequencing identified the bacterium as Ottowia massiliensis sp.nov. (LT960589.1). Antimicrobial sensitivity tests showed high activity against most ophthalmic drugs. Conclusions In the case described here, we discuss the diagnosis and treatment strategies for eye infections caused by Ottowia massiliensis sp.nov., laying the foundation for improving clinical and laboratory awareness of this bacterium.https://doi.org/10.1186/s12886-025-04007-wOttowia massiliensis Sp.nov.Bacterial canaliculitisBacterial identificationAntimicrobial sensitivity testing |
| spellingShingle | Yuxuan Wu Hua Sun Min Kang Kexin Chen Qingfeng Liang Xinxin Lu A case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.nov BMC Ophthalmology Ottowia massiliensis Sp.nov. Bacterial canaliculitis Bacterial identification Antimicrobial sensitivity testing |
| title | A case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.nov |
| title_full | A case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.nov |
| title_fullStr | A case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.nov |
| title_full_unstemmed | A case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.nov |
| title_short | A case report of bacterial canaliculitis caused by Ottowia massiliensis Sp.nov |
| title_sort | case report of bacterial canaliculitis caused by ottowia massiliensis sp nov |
| topic | Ottowia massiliensis Sp.nov. Bacterial canaliculitis Bacterial identification Antimicrobial sensitivity testing |
| url | https://doi.org/10.1186/s12886-025-04007-w |
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