Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand test
Muscle power is a better indicator of musculoskeletal health and functional capacity than muscle strength. The Load-Velocity (L-V) relationship provides a method for assessing muscle function during dynamic multi-joint movements, making it valuable for identifying age-related neuromuscular decline....
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Experimental Gerontology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0531556525000968 |
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| author | Daniel Jiménez-Lupión Ignacio Chirosa-Ríos Rodrigo Lizama-Pérez Luis Chirosa-Ríos Daniel Jerez-Mayorga |
| author_facet | Daniel Jiménez-Lupión Ignacio Chirosa-Ríos Rodrigo Lizama-Pérez Luis Chirosa-Ríos Daniel Jerez-Mayorga |
| author_sort | Daniel Jiménez-Lupión |
| collection | DOAJ |
| description | Muscle power is a better indicator of musculoskeletal health and functional capacity than muscle strength. The Load-Velocity (L-V) relationship provides a method for assessing muscle function during dynamic multi-joint movements, making it valuable for identifying age-related neuromuscular decline. This study aimed to examine the relationship between variables derived from the L-V relationship (L0, V0, and Aline) obtained during the loaded sit-to-stand test and various muscle performance indices, including knee extension peak force (KEPF) and various muscle quality indices (MQI).A total of 113 participants (49 middle-aged adults and 64 older adults; age = 61 ± 9.92 years) performed the loaded 5-Sit-To-Stand using Functional Electromechanical Dynamometry. L-V variables were calculated, and their relationships with indicators of muscle performance and quality were analyzed. The impact of age on these variables was also evaluated. The results showed a high positive correlation between Aline and KEPF, MQIEquation1, MQIEquation2 and MQIEquation3 (rs = 0.56–0.59, p ≤0.001–0.01), and between V0 and KEFP (rs = 0.51, p < 0.001). Older adults exhibited significantly lower L0 compared to middle-aged adults (76.86 ± 29.74 kg vs. 94.62 ± 35.69 kg, p = 0.007), as well as lower V0 (0.92 ± 0.28 m·s−1 vs. 1.22 ± 0.19 m·s−1, p < 0.001) and Aline values (35.39 ± 18.95 kg·m·s−1 vs. 57.75 ± 23.84 kg·m·s−1, p < 0.001). These findings suggest that L-V variables are valuable indicators for assessing muscle function deterioration and guiding training interventions, providing a more comprehensive and sensitive assessment of muscle quality and functional status in aging populations. |
| format | Article |
| id | doaj-art-1d56d284ea4349eabca4feb3368cebbd |
| institution | DOAJ |
| issn | 1873-6815 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Experimental Gerontology |
| spelling | doaj-art-1d56d284ea4349eabca4feb3368cebbd2025-08-20T03:21:51ZengElsevierExperimental Gerontology1873-68152025-07-0120611276710.1016/j.exger.2025.112767Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand testDaniel Jiménez-Lupión0Ignacio Chirosa-Ríos1Rodrigo Lizama-Pérez2Luis Chirosa-Ríos3Daniel Jerez-Mayorga4Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, SpainDepartment of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, SpainDepartamento de Ciencias Morfológicas, Facultad de Medicina y Ciencia, Universidad San Sebastián, Lientur 1457, Concepción 4080871, Chile; Departamento de Anatomía Normal y Medicina Legal, Facultad de Medicina, Universidad de Concepción, Concepción, ChileDepartment of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, SpainDepartment of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, Spain; Exercise and Rehabilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago, Chile; Corresponding author at: Carretera de Alfacar 21, 18011 Granada, Spain.Muscle power is a better indicator of musculoskeletal health and functional capacity than muscle strength. The Load-Velocity (L-V) relationship provides a method for assessing muscle function during dynamic multi-joint movements, making it valuable for identifying age-related neuromuscular decline. This study aimed to examine the relationship between variables derived from the L-V relationship (L0, V0, and Aline) obtained during the loaded sit-to-stand test and various muscle performance indices, including knee extension peak force (KEPF) and various muscle quality indices (MQI).A total of 113 participants (49 middle-aged adults and 64 older adults; age = 61 ± 9.92 years) performed the loaded 5-Sit-To-Stand using Functional Electromechanical Dynamometry. L-V variables were calculated, and their relationships with indicators of muscle performance and quality were analyzed. The impact of age on these variables was also evaluated. The results showed a high positive correlation between Aline and KEPF, MQIEquation1, MQIEquation2 and MQIEquation3 (rs = 0.56–0.59, p ≤0.001–0.01), and between V0 and KEFP (rs = 0.51, p < 0.001). Older adults exhibited significantly lower L0 compared to middle-aged adults (76.86 ± 29.74 kg vs. 94.62 ± 35.69 kg, p = 0.007), as well as lower V0 (0.92 ± 0.28 m·s−1 vs. 1.22 ± 0.19 m·s−1, p < 0.001) and Aline values (35.39 ± 18.95 kg·m·s−1 vs. 57.75 ± 23.84 kg·m·s−1, p < 0.001). These findings suggest that L-V variables are valuable indicators for assessing muscle function deterioration and guiding training interventions, providing a more comprehensive and sensitive assessment of muscle quality and functional status in aging populations.http://www.sciencedirect.com/science/article/pii/S0531556525000968Muscle powerLoad-velocity profilingMuscle qualityAgingOlder adults |
| spellingShingle | Daniel Jiménez-Lupión Ignacio Chirosa-Ríos Rodrigo Lizama-Pérez Luis Chirosa-Ríos Daniel Jerez-Mayorga Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand test Experimental Gerontology Muscle power Load-velocity profiling Muscle quality Aging Older adults |
| title | Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand test |
| title_full | Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand test |
| title_fullStr | Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand test |
| title_full_unstemmed | Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand test |
| title_short | Assessment of muscle function deterioration in aging populations: Insights from the load-velocity relationship during the loaded sit-to-stand test |
| title_sort | assessment of muscle function deterioration in aging populations insights from the load velocity relationship during the loaded sit to stand test |
| topic | Muscle power Load-velocity profiling Muscle quality Aging Older adults |
| url | http://www.sciencedirect.com/science/article/pii/S0531556525000968 |
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