Expression Characteristics and Prognostic Value of KLRG2 in Endometrial Cancer: A Comprehensive Analysis Based on Multi-Omics Data

Expression Characteristics and Prognostic Value of KLRG2 in Endometrial Cancer: A Comprehensive Analysis Based on Multi-Omics Data

<b>Background</b>: Endometrial cancer (EC) remains a major gynecologic malignancy with limited biomarkers for risk stratification. While killer cell lectin-like receptor G2 (KLRG2) exhibits oncogenic properties in other cancers, its clinical significance and mechanistic roles in EC are u...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xiaoyan Huang, Ailian Li, Dianbo Xu
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Biomedicines
Subjects:	endometrial neoplasms KLRG2 biomarkers tumor microenvironment prognosis methylation
Online Access:	https://www.mdpi.com/2227-9059/13/7/1592
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

KLRG1 expression induces functional exhaustion of NK cells in colorectal cancer patients
by: Cairui Xu, et al.
Published: (2025-05-01)

Integrating multi-omics data to optimize immunotherapy in endometrial cancer: a comprehensive study
by: Xin Guan, et al.
Published: (2025-06-01)

Cervicovaginal lavages uncover growth factors as key biomarkers for early diagnosis and prognosis of endometrial cancer
by: Hannah J. Harris, et al.
Published: (2024-11-01)

Integrative Bioinformatic Analysis of Cellular Senescence Genes in Ovarian Cancer: Molecular Subtyping, Prognostic Risk Stratification, and Chemoresistance Prediction
by: Ailian Li, et al.
Published: (2025-04-01)

Prognostic parameters in FIGO stage I endometrial carcinoma of endometrioid type
by: Stanojević Zorica, et al.
Published: (2006-01-01)

Lipid-Metabolism-Related Gene Signature Predicts Prognosis and Immune Microenvironment Alterations in Endometrial Cancer
by: Zhangxin Wu, et al.
Published: (2025-04-01)

Predicting immunotherapy efficacy in endometrial cancer: focus on the tumor microenvironment
by: Liubov A. Tashireva, et al.
Published: (2025-01-01)

A novel mitochondrial-related risk model for predicting prognosis and immune checkpoint blockade therapy response in uterine corpus endometrial carcinoma
by: Ru-Gen Liao, et al.
Published: (2025-01-01)

Prognostic value and immune infiltration analysis of a novel lactylation-related gene signature in endometrial cancer
by: Liqin Gu, et al.
Published: (2025-06-01)

Reviewing prognostic factors associated with recurrence in clinically early-stage low-risk endometrial cancer
by: Thales Paulo Batista, et al.
Published: (2022-10-01)

The Prognosis Prediction Model for Endometrial Cancer Based on DNA Methylation Signature
by: Ran Ran, et al.
Published: (2025-06-01)

Prognostic significance of tumor budding in endometrial cancer: clinicopathological insights
by: Ashi Dubey, et al.
Published: (2025-04-01)

CD8<sup>+</sup>CD28<sup>+</sup>PD1<sup>−</sup> T Cells as a Prognostic Biomarker in Endometrial Cancer
by: Yufei Nie, et al.
Published: (2025-02-01)

Single-cell RNA-seq reveals FGF12 as a prognostic biomarker in low-grade endometrial stromal sarcoma
by: Yu Miao, et al.
Published: (2024-11-01)

Expression and prognostic value of EGF-like domain multiple 6 in uterine corpus endometrial carcinoma and its correlation with immune cell infiltration
by: Qiannan Li, et al.
Published: (2025-07-01)

Prognostic value and immunotherapy analysis of immune cell-related genes in laryngeal cancer
by: Sen Zhang, et al.
Published: (2025-04-01)

Association of stromal tumor-infiltrating lymphocytes with clinicopathological parameters in endometrial cancer
by: Sana Ahuja, et al.
Published: (2024-12-01)

Prognostic significance of atypical/hybrid forms of EpCAM+CD45+ cells in the blood of patients with endometrial cancer
by: E. V. Kaigorodova, et al.
Published: (2023-08-01)

Identification of clusters related to programmed cell death and potential prognostic biomarkers for immunotherapy response in endometrial cancer
by: Shan Lu, et al.
Published: (2025-07-01)

EFNB1 drives glioma progression and shapes the immune microenvironment: a potential prognostic biomarker
by: Yungui Zheng, et al.
Published: (2025-02-01)

Cyclin D2 – a potential biomarker in uterine corpus endometrial carcinoma through methylation chip and bioinformatic analysis
by: Lizhen Wang, et al.
Published: (2025-07-01)

LIN28B promotes the progression of endometrial cancer through upregulating MYC and correlates with immune microenvironment
by: Yuchao Diao, et al.
Published: (2025-07-01)

Comprehensive analyses of telomerase component DKC1 and its association with clinical, molecular and immune landscapes in uterine corpus endometrial carcinoma
by: Chenxi Sun, et al.
Published: (2025-05-01)

Risk Factors for Endometrial Cancer in the World: A Narrative Review of the Recent Literature
by: Hamid Salehiniya, et al.
Published: (2024-07-01)

Identification of CWH43 as a novel prognostic biomarker and therapeutic target in clear cell renal cell carcinoma by a multi-omics approach and correlation with autophagy progression
by: Ailian Wu, et al.
Published: (2025-06-01)

Novel molecular classification of endometrial cancer - current and future clinical implications
by: Mandić Aljoša, et al.
Published: (2023-01-01)

Prevalence and characteristics of endometrial polyps in patients with abnormal uterine bleeding
by: Đorđević Biljana, et al.
Published: (2008-01-01)

Identification of immune-related cervical cancer prognostic biomarkers and construction of prognostic model based on tumor microenvironment
by: Qiufang Bao, et al.
Published: (2025-04-01)

CEBPB promotes transformation of endometrial complex atypical hyperplasia to endometrial cancer
by: Jiahong Tan, et al.
Published: (2025-06-01)

RAD51 expression and prognostic impact in patients with stomach adenocarcinoma
by: Baiyu Jian, et al.
Published: (2025-04-01)

Multi-omics dissection of CPNE1 reveals its prognostic value and immune-regulatory function in liver cancer
by: Liu Liu, et al.
Published: (2025-08-01)

CLEC3B as a Prognostic and Immunological Biomarker in Pan-Cancer: Multi-Omics Profiling and Validation in Pancreatic Cancer and Exosomes
by: Nan K, et al.
Published: (2025-05-01)

The Accuracy of Endometrial Sampling and Clinical Affecting Factors as a Predictor of Final Surgical Pathology in Endometrial Cancer
by: Lukkana Promwattanaphan, et al.
Published: (2022-04-01)

Evaluation of pyroptosis-associated genes in endometrial cancer utilizing a 101-combination machine learning framework and multi-omics data
by: Li Juan Huang, et al.
Published: (2025-06-01)

Prognostic value of lymphocyte-to-monocyte ratio in patients with endometrial cancer: an updated systematic review and meta-analysis
by: Zijing Huang, et al.
Published: (2025-06-01)

Mortality from endometrial cancer in female population of Belgrade
by: Pantović Vesna R., et al.
Published: (2004-01-01)

Significance of Gelsolin Superfamily Genes in Diagnosis, Prognosis and Immune Microenvironment Regulation for Endometrial Cancer
by: Senwei Jiang, et al.
Published: (2025-02-01)

The role of laminins in cancer pathobiology: a comprehensive review
by: Elena Nonnast, et al.
Published: (2025-01-01)

Metabolism-Related Genes SMOX and SUCLG2 as Immunological and Prognostic Biomarkers in Colorectal Cancer: A Pan-Cancer Analysis
by: Zuming Xiong, et al.
Published: (2025-06-01)

CCDC138 overexpression predicts poor prognosis and highlights ciliopathy-linked mechanisms in uterine corpus endometrial carcinoma
by: Aiping Wang, et al.
Published: (2025-08-01)