Molecular mechanisms underlying Fagopyrum dibotrys-derived nanovesicles induced ferroptosis in hepatocellular carcinoma: a dual-pathway analysis of lipid peroxidation and mitochondrial damage

Molecular mechanisms underlying Fagopyrum dibotrys-derived nanovesicles induced ferroptosis in hepatocellular carcinoma: a dual-pathway analysis of lipid peroxidation and mitochondrial damage

BackgroundHepatocellular carcinoma (HCC) is a prevalent malignant tumor globally, with high incidence and mortality rates that seriously endanger human health. While traditional therapeutic approaches have demonstrated some efficacy in controlling disease progression, they are still fraught with num...

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Bibliographic Details
Main Authors: Ling Wu, Hongyao Chen, Jingting Zhang, Jincheng Tang, Zhibin Wang, Peisen Xue, Wenhui Gao, Renyi Yang, Puhua Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
Fagopyrum dibotrys
nanovesicles
hepatocellular carcinoma
ferroptosis
in vitro and in vivo experiments
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1636149/full
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