Molecular docking studies and molecular dynamic simulation analysis: To identify novel ATP-competitive inhibition of Glycogen synthase kinase-3β for Alzheimer’s disease [version 3; peer review: 2 approved, 1 approved with reservations, 1 not approved]
Background The discovery of an ideal and effective therapy is urgently required for the treatment of Alzheimer’s disease (AD). The main pathological hallmarks of Alzheimer’s disease that appear before the clinical symptoms are neurofibrillary tangles, amyloid plaques, brain inflammation, and neurona...
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| Main Authors: | Suggala Ramya Shri, Yogendra Nayak, Sreedhara Ranganath Pai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2025-05-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | https://f1000research.com/articles/13-773/v3 |
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