Rothia-Associated Meningitis in a Patient With HIV: A Case Report
A 47-year-old man with HIV, off antiretroviral therapy for 4 months since losing insurance coverage, presented to the emergency department after he was found unresponsive with blood around the mouth. A seizure was suspected, and cerebrospinal fluid culture grew Rothia mucilaginosa, Rothia dentocario...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2025-07-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2025.0321 |
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| Summary: | A 47-year-old man with HIV, off antiretroviral therapy for 4 months since losing insurance coverage, presented to the emergency department after he was found unresponsive with blood around the mouth. A seizure was suspected, and cerebrospinal fluid culture grew Rothia mucilaginosa, Rothia dentocariosa, and Streptococcus viridans. While it is well established that HIV-infected individuals are at higher risk for opportunistic infections, reports identifying commensal oral microbiota as the source of invasive disease are rare. This case underscores the importance of recognizing the pathogenic potential of atypical pathogens and diverse clinical presentations of meningitis in immunocompromised patients. |
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| ISSN: | 2767-7664 |