Influence of Cell Seeding Density and Material Stiffness on Chondrogenesis of Human Stem Cells Within Soft Hydrogels, Without the Use of Exogenous Growth Factors

Influence of Cell Seeding Density and Material Stiffness on Chondrogenesis of Human Stem Cells Within Soft Hydrogels, Without the Use of Exogenous Growth Factors

Mesenchymal stem cells (MSCs) can differentiate into chondrocytes provided with the appropriate environmental cues. In this study, we loaded human adipose-derived stem cells (hAdMSCs) into collagen/alginate hydrogels, which have been shown to induce chondrogenesis in ovine bone marrow stem cells wit...

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Bibliographic Details
Main Authors: Arianna De Mori, Nadide Aydin, Giada Lostia, Alessia Manca, Gordon Blunn, Marta Roldo
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Gels
Subjects:
alginate
collagen
hydrogels
chondrogenesis
Online Access:https://www.mdpi.com/2310-2861/11/3/213
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