Genome-wide CRISPR screening identifies LRP1 as an entry factor for SFTSV

Genome-wide CRISPR screening identifies LRP1 as an entry factor for SFTSV

Abstract Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by the SFTS virus (SFTSV), which has high mortality rates and poses a significant threat to public health. To identify potential therapeutic targets against SFTSV, we conduct genome-wide knockout scr...

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Bibliographic Details
Main Authors: Chen Xing, Cong Zhang, Zhihao Xu, Yajie Wang, Wanqing Lu, Xiaohan Liu, Yingying Zhang, Jingyuan Ma, Shuqi Yang, Yinan Du, Gang Xu, Yan Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59305-0
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