Medicinal evaluation and molecular docking study of osajin as an anti-inflammatory, antioxidant, and antiapoptotic agent against sepsis-associated acute kidney injury in rats

Medicinal evaluation and molecular docking study of osajin as an anti-inflammatory, antioxidant, and antiapoptotic agent against sepsis-associated acute kidney injury in rats

Despite efforts to find effective drugs for sepsis-associated acute kidney injury (SA-AKI), mortality rates in patients with SA-AKI have not decreased. Our study evaluated the protective effects of isoflavone osajin (OSJ) on SA-AKI in rats by targeting inflammation, oxidative stress, and apoptosis,...

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Bibliographic Details
Main Authors: Mohammad Alhilal, Huseyin Serkan Erol, Serkan Yildirim, Ahmet Cakir, Murat Koc, Suzan Alhilal, Esra Dereli, Omer Alkanoglu, Volkan Ay, Ismail Can, Mesut Bunyami Halici
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
Apoptosis
inflammation
osajin
oxidative stress
SA-AKI
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2379008
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