High-Throughput Screening for Known Mutations by Automated Analysis of Single Sequencing Reactions
This work shows that single sequencing reactions analyzed on an automated DNA sequencer can be an efficient way of screening PCR products for known mutations. We have analyzed a mutation in exon 10 of the human aromatase gene and show that an unambiguous genotype could be elucidated in more than 90%...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
1998-05-01
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| Series: | BioTechniques |
| Online Access: | https://www.future-science.com/doi/10.2144/98245dt04 |
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