Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case Report
Introduction: Several studies have proposed a relationship between the coronavirus disease 2019 (COVID-19)-induced cytokine storm and prohibitive effects on the musculoskeletal system, including increased risk of fracture, osteoporosis, and impaired bone healing. To our knowledge, this is the first...
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| Format: | Article |
| Language: | English |
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Indian Orthopaedic Research Group
2025-02-01
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| Series: | Journal of Orthopaedic Case Reports |
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| Online Access: | https://jocr.co.in/wp/2025/02/01/non-union-of-a-tibial-plafond-fracture-in-a-covid-positive-patient-a-case-report/ |
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| _version_ | 1849421656484741120 |
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| author | Amy Singleton Anthony J Mancuso II Samuel G Eaddy Seth Phillips |
| author_facet | Amy Singleton Anthony J Mancuso II Samuel G Eaddy Seth Phillips |
| author_sort | Amy Singleton |
| collection | DOAJ |
| description | Introduction:
Several studies have proposed a relationship between the coronavirus disease 2019 (COVID-19)-induced cytokine storm and prohibitive effects on the musculoskeletal system, including increased risk of fracture, osteoporosis, and impaired bone healing. To our knowledge, this is the first known case report involving a fracture non-union concomitant with COVID-19 infection and apparent cytokine storm.
Case Report:
A 47-year-old male presented with an open pilon fracture of the left ankle after falling off a 6-foot ladder. At his 4-month post-operative follow-up, the patient attempted to ambulate without his cam boot for the 1st time, causing acute displacement of his poorly healed tibia fracture. A non-union laboratory workup demonstrated elevated inflammatory markers indicative of septic non-union; however, the patient also tested positive for severe acute respiratory syndrome coronavirus 2 at this time. Because of this, antibiotic treatment was not initiated due to suspicion of a cytokine storm. One month later, the patient’s inflammatory markers had decreased and he underwent revision surgery.
Conclusion:
This case underscores the potential impact of COVID-19 on fracture healing and the importance of vigilant monitoring and differential diagnosis in managing non-union in COVID-19-positive patients. |
| format | Article |
| id | doaj-art-1cff7ffe2cfa450d86a9b053c3ca53b4 |
| institution | Kabale University |
| issn | 2250-0685 2321-3817 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Indian Orthopaedic Research Group |
| record_format | Article |
| series | Journal of Orthopaedic Case Reports |
| spelling | doaj-art-1cff7ffe2cfa450d86a9b053c3ca53b42025-08-20T03:31:24ZengIndian Orthopaedic Research GroupJournal of Orthopaedic Case Reports2250-06852321-38172025-02-01152111510.13107/jocr.2025.v15.i02.5210Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case ReportAmy SingletonAnthony J Mancuso IISamuel G EaddySeth PhillipsIntroduction: Several studies have proposed a relationship between the coronavirus disease 2019 (COVID-19)-induced cytokine storm and prohibitive effects on the musculoskeletal system, including increased risk of fracture, osteoporosis, and impaired bone healing. To our knowledge, this is the first known case report involving a fracture non-union concomitant with COVID-19 infection and apparent cytokine storm. Case Report: A 47-year-old male presented with an open pilon fracture of the left ankle after falling off a 6-foot ladder. At his 4-month post-operative follow-up, the patient attempted to ambulate without his cam boot for the 1st time, causing acute displacement of his poorly healed tibia fracture. A non-union laboratory workup demonstrated elevated inflammatory markers indicative of septic non-union; however, the patient also tested positive for severe acute respiratory syndrome coronavirus 2 at this time. Because of this, antibiotic treatment was not initiated due to suspicion of a cytokine storm. One month later, the patient’s inflammatory markers had decreased and he underwent revision surgery. Conclusion: This case underscores the potential impact of COVID-19 on fracture healing and the importance of vigilant monitoring and differential diagnosis in managing non-union in COVID-19-positive patients.https://jocr.co.in/wp/2025/02/01/non-union-of-a-tibial-plafond-fracture-in-a-covid-positive-patient-a-case-report/pilon fracturetibial plafond fracturedelayed unionnon-unioncoronavirus disease 19cytokine stormrevision |
| spellingShingle | Amy Singleton Anthony J Mancuso II Samuel G Eaddy Seth Phillips Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case Report Journal of Orthopaedic Case Reports pilon fracture tibial plafond fracture delayed union non-union coronavirus disease 19 cytokine storm revision |
| title | Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case Report |
| title_full | Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case Report |
| title_fullStr | Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case Report |
| title_full_unstemmed | Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case Report |
| title_short | Non-union of a Tibial Plafond Fracture in a COVID-Positive Patient: A Case Report |
| title_sort | non union of a tibial plafond fracture in a covid positive patient a case report |
| topic | pilon fracture tibial plafond fracture delayed union non-union coronavirus disease 19 cytokine storm revision |
| url | https://jocr.co.in/wp/2025/02/01/non-union-of-a-tibial-plafond-fracture-in-a-covid-positive-patient-a-case-report/ |
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