Clinical and pharmacogenomic predictors of survival in tamoxifen treated breast cancer female patients: a real-world study

Abstract Aim To investigate the impact of tamoxifen dose, CYP2D6 inhibitors, CYP2D6*4 genotype, and non-genetic parameters on the outcomes of tamoxifen treated female breast cancer patients. Method We retrospectively included 3218 female patients who initiated tamoxifen following a diagnosis of brea...

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Bibliographic Details
Main Authors: Abdullah R. Al-Matrafi, Khaled F. Bedair, Sundararajan Srinivasan, Colin Palmer, Archie Campbell, Caroline Hayward, Ewan R. Pearson, Russell D. Petty
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-14162-4
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