Differentiation and correlation of regional uptake heterogeneity with cardiac dysfunction in biopsy-proven transthyretin amyloid cardiomyopathy using quantitative single-photon emission computed tomography/computed tomography: a single-center, cross-sectional study

Differentiation and correlation of regional uptake heterogeneity with cardiac dysfunction in biopsy-proven transthyretin amyloid cardiomyopathy using quantitative single-photon emission computed tomography/computed tomography: a single-center, cross-sectional study

Abstract Background Cardiac amyloidosis requires quantitative assessment using technetium-99m pyrophosphate (99mTc-PYP) single-photon emission computed tomography (SPECT)/computed tomography (CT) for adequate discrimination and evaluation of disease extent. This study aimed to evaluate the utility o...

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Bibliographic Details
Main Authors: Masakazu Tsujimoto, Hideki Kawai, Shingo Tanahashi, Masayoshi Sarai, Yasuki Asada, Hideo Izawa
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:EJNMMI Research
Subjects:
Amyloidosis
Single-photon emission computed tomography
Non-invasive diagnosis
Online Access:https://doi.org/10.1186/s13550-025-01292-w
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