Impact of Sjögren’s disease on quality of sexual life using the Qualisex score
Objective This study aimed to assess the impact of Sjögren disease (SjD) on the quality of sexual life and its determinants using the Qualisex questionnaire.Methods The Qualisex questionnaire was administered to participants within the ASSESS cohort, a French national multicentric prospective cohort...
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BMJ Publishing Group
2025-01-01
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| Series: | RMD Open |
| Online Access: | https://rmdopen.bmj.com/content/11/1/e004693.full |
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| author | Eric Hachulla Xavier Mariette Jacques-Eric Gottenberg Philippe Dieude Aleth Perdriger Emanuelle Dernis Marion Couderc Raphaele Seror Gaetane Nocturne Rakiba Belkhir Valérie Devauchelle-Pensec Veronique Le Guern Alexandra Kachaner Sophie Berville |
| author_facet | Eric Hachulla Xavier Mariette Jacques-Eric Gottenberg Philippe Dieude Aleth Perdriger Emanuelle Dernis Marion Couderc Raphaele Seror Gaetane Nocturne Rakiba Belkhir Valérie Devauchelle-Pensec Veronique Le Guern Alexandra Kachaner Sophie Berville |
| author_sort | Eric Hachulla |
| collection | DOAJ |
| description | Objective This study aimed to assess the impact of Sjögren disease (SjD) on the quality of sexual life and its determinants using the Qualisex questionnaire.Methods The Qualisex questionnaire was administered to participants within the ASSESS cohort, a French national multicentric prospective cohort of individuals with SjD. Patients’ characteristics and psychometric evaluations were also collected.Results Among the 395 patients of the cohort, 92 (23%) completed the questionnaire, with a median age of 56 (44–59) years and a female ratio of 92% (85/92). The median Qualisex score was 3.4 (1.1–5.9).Comparing the first and last quartiles of the Qualisex score, a worst sexual satisfaction was associated with older age (median (IQR) 58 (52–65) vs 52 (41–56) years, p=0.005), higher EULAR Sjögren’s disease Patient Reported Index (ESSPRI) (6.8 (5.7–7.7) vs 4.3 (2.8–5.3), p<0.0001) lower SF-36 mental and physical scores (respectively, 43 (38–46) vs 49 (47–53), p=0.0035 and 31 (29–35) vs 35 (30–37), p=0.035), higher Depression and Anxiety scores (HADS) (respectively, 9 (7–11) vs 2 (1–4), p<0.0001 and 11 (8–14) vs 7 (4–10), p=0.006). Interestingly, EULAR Sjögren’s disease Disease Activity Index (ESSDAI) score did not differ significantly (4 (1–10) vs 2.5 (1.8–4), p=0.35). In a multivariable analysis, the Qualisex score remained strongly associated with a higher HADS depression score and, to a lesser extent, with a higher ESSPRI. The inability to obtain a score was associated with older age.Conclusion In SjD patients, sexual satisfaction assessed with the Qualisex score, was strongly associated with depression and, to lesser extent, with ESSPRI, but not with systemic activity. |
| format | Article |
| id | doaj-art-1cf112e29b0a40769ab43ff42be09f69 |
| institution | Kabale University |
| issn | 2056-5933 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMJ Publishing Group |
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| series | RMD Open |
| spelling | doaj-art-1cf112e29b0a40769ab43ff42be09f692025-01-23T06:15:11ZengBMJ Publishing GroupRMD Open2056-59332025-01-0111110.1136/rmdopen-2024-004693Impact of Sjögren’s disease on quality of sexual life using the Qualisex scoreEric Hachulla0Xavier Mariette1Jacques-Eric Gottenberg2Philippe Dieude3Aleth Perdriger4Emanuelle Dernis5Marion Couderc6Raphaele Seror7Gaetane Nocturne8Rakiba Belkhir9Valérie Devauchelle-Pensec10Veronique Le Guern11Alexandra Kachaner12Sophie Berville13Lille University School of Medicine, Lille, FranceRheumatology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux universitaires Paris-Sud – Hôpital Bicêtre, Le Kremlin Bicêtre, FranceRheumatology, Hopitaux universitaires de Strasbourg, Strasbourg, FranceRheumatology, APHP, Paris, FrancePolyclinique du Maine, Laval, FranceRheumatology, Le Mans Hospital, Le Mans, FranceRheumatology, University Hospital Centre Clermont-Ferrand, Clermont-Ferrand, FranceRheumatology, Hôpitaux universitaires Paris-Sud, Le Kremlin Bicêtre, FranceUniversite Paris Sud Faculte de Medecine, Le Kremlin-Bicetre, FranceDepartment of Rheumatology, Hôpital Bicêtre, Le Kremlin-Bicetre, FranceRheumatology, Brest University and La Cavale Blanche Hospital, Brest, FranceDepartment of Internal Medicine, APHP, Paris, FranceHospital Bicetre, Le Kremlin-Bicetre, FranceCabinet de gynécologie 2 avenue René coty, Paris, FranceObjective This study aimed to assess the impact of Sjögren disease (SjD) on the quality of sexual life and its determinants using the Qualisex questionnaire.Methods The Qualisex questionnaire was administered to participants within the ASSESS cohort, a French national multicentric prospective cohort of individuals with SjD. Patients’ characteristics and psychometric evaluations were also collected.Results Among the 395 patients of the cohort, 92 (23%) completed the questionnaire, with a median age of 56 (44–59) years and a female ratio of 92% (85/92). The median Qualisex score was 3.4 (1.1–5.9).Comparing the first and last quartiles of the Qualisex score, a worst sexual satisfaction was associated with older age (median (IQR) 58 (52–65) vs 52 (41–56) years, p=0.005), higher EULAR Sjögren’s disease Patient Reported Index (ESSPRI) (6.8 (5.7–7.7) vs 4.3 (2.8–5.3), p<0.0001) lower SF-36 mental and physical scores (respectively, 43 (38–46) vs 49 (47–53), p=0.0035 and 31 (29–35) vs 35 (30–37), p=0.035), higher Depression and Anxiety scores (HADS) (respectively, 9 (7–11) vs 2 (1–4), p<0.0001 and 11 (8–14) vs 7 (4–10), p=0.006). Interestingly, EULAR Sjögren’s disease Disease Activity Index (ESSDAI) score did not differ significantly (4 (1–10) vs 2.5 (1.8–4), p=0.35). In a multivariable analysis, the Qualisex score remained strongly associated with a higher HADS depression score and, to a lesser extent, with a higher ESSPRI. The inability to obtain a score was associated with older age.Conclusion In SjD patients, sexual satisfaction assessed with the Qualisex score, was strongly associated with depression and, to lesser extent, with ESSPRI, but not with systemic activity.https://rmdopen.bmj.com/content/11/1/e004693.full |
| spellingShingle | Eric Hachulla Xavier Mariette Jacques-Eric Gottenberg Philippe Dieude Aleth Perdriger Emanuelle Dernis Marion Couderc Raphaele Seror Gaetane Nocturne Rakiba Belkhir Valérie Devauchelle-Pensec Veronique Le Guern Alexandra Kachaner Sophie Berville Impact of Sjögren’s disease on quality of sexual life using the Qualisex score RMD Open |
| title | Impact of Sjögren’s disease on quality of sexual life using the Qualisex score |
| title_full | Impact of Sjögren’s disease on quality of sexual life using the Qualisex score |
| title_fullStr | Impact of Sjögren’s disease on quality of sexual life using the Qualisex score |
| title_full_unstemmed | Impact of Sjögren’s disease on quality of sexual life using the Qualisex score |
| title_short | Impact of Sjögren’s disease on quality of sexual life using the Qualisex score |
| title_sort | impact of sjogren s disease on quality of sexual life using the qualisex score |
| url | https://rmdopen.bmj.com/content/11/1/e004693.full |
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