Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical Sensing

Copper-based materials, renowned for their redox versatility and conductivity, have extensive applications in electrochemical sensing. Herein, we construct stable Cu<sup>+</sup>/Cu<sup>2+</sup> interfaces within dual-valence copper nanostructures to achieve enhanced sensitivi...

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Main Authors: Zhipeng Yu, Pengxu Yan, Yilei Sheng, Chengwei Zhang, Zhun Qiao, Qikui Fan, Chuncai Kong, Zhimao Yang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Nanomaterials
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Online Access:https://www.mdpi.com/2079-4991/14/24/2000
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author Zhipeng Yu
Pengxu Yan
Yilei Sheng
Chengwei Zhang
Zhun Qiao
Qikui Fan
Chuncai Kong
Zhimao Yang
author_facet Zhipeng Yu
Pengxu Yan
Yilei Sheng
Chengwei Zhang
Zhun Qiao
Qikui Fan
Chuncai Kong
Zhimao Yang
author_sort Zhipeng Yu
collection DOAJ
description Copper-based materials, renowned for their redox versatility and conductivity, have extensive applications in electrochemical sensing. Herein, we construct stable Cu<sup>+</sup>/Cu<sup>2+</sup> interfaces within dual-valence copper nanostructures to achieve enhanced sensitivity in glucose sensing. By employing a hydrolysis method to tune Cu<sup>2+</sup>/Cu<sup>+</sup> ratios precisely, we achieved an optimal electrochemical interface with heightened stability and reactivity. The Cu<sup>+</sup>/Cu<sup>2+</sup> interface-based flexible electrode demonstrated excellent glucose sensitivity (332.4 µA mmol/L<sup>−1</sup> cm<sup>−2</sup> at +0.65 V), wide linear range (up to 10 mmol), a low detection limit of 1.02 nmol/L, and strong selectivity, including detection in human sweat, making this study significant for advanced electrochemical sensors.
format Article
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institution DOAJ
issn 2079-4991
language English
publishDate 2024-12-01
publisher MDPI AG
record_format Article
series Nanomaterials
spelling doaj-art-1ce4a25f596b408ebcac38be43dc934d2025-08-20T02:57:17ZengMDPI AGNanomaterials2079-49912024-12-011424200010.3390/nano14242000Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical SensingZhipeng Yu0Pengxu Yan1Yilei Sheng2Chengwei Zhang3Zhun Qiao4Qikui Fan5Chuncai Kong6Zhimao Yang7Ministry of Education Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Functional Materials and Mesoscopic Physics, School of Physics, Xi’an Jiaotong University, Xi’an 710049, ChinaMinistry of Education Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Functional Materials and Mesoscopic Physics, School of Physics, Xi’an Jiaotong University, Xi’an 710049, ChinaMinistry of Education Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Functional Materials and Mesoscopic Physics, School of Physics, Xi’an Jiaotong University, Xi’an 710049, ChinaMinistry of Education Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Functional Materials and Mesoscopic Physics, School of Physics, Xi’an Jiaotong University, Xi’an 710049, ChinaXi’an Rare Metal Materials Institute Co., Ltd., Xi’an 710016, ChinaMinistry of Education Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Functional Materials and Mesoscopic Physics, School of Physics, Xi’an Jiaotong University, Xi’an 710049, ChinaMinistry of Education Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Functional Materials and Mesoscopic Physics, School of Physics, Xi’an Jiaotong University, Xi’an 710049, ChinaMinistry of Education Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Functional Materials and Mesoscopic Physics, School of Physics, Xi’an Jiaotong University, Xi’an 710049, ChinaCopper-based materials, renowned for their redox versatility and conductivity, have extensive applications in electrochemical sensing. Herein, we construct stable Cu<sup>+</sup>/Cu<sup>2+</sup> interfaces within dual-valence copper nanostructures to achieve enhanced sensitivity in glucose sensing. By employing a hydrolysis method to tune Cu<sup>2+</sup>/Cu<sup>+</sup> ratios precisely, we achieved an optimal electrochemical interface with heightened stability and reactivity. The Cu<sup>+</sup>/Cu<sup>2+</sup> interface-based flexible electrode demonstrated excellent glucose sensitivity (332.4 µA mmol/L<sup>−1</sup> cm<sup>−2</sup> at +0.65 V), wide linear range (up to 10 mmol), a low detection limit of 1.02 nmol/L, and strong selectivity, including detection in human sweat, making this study significant for advanced electrochemical sensors.https://www.mdpi.com/2079-4991/14/24/2000dual-valence copper compositeinterfacesmetal oxideglucosedetection
spellingShingle Zhipeng Yu
Pengxu Yan
Yilei Sheng
Chengwei Zhang
Zhun Qiao
Qikui Fan
Chuncai Kong
Zhimao Yang
Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical Sensing
Nanomaterials
dual-valence copper composite
interfaces
metal oxide
glucose
detection
title Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical Sensing
title_full Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical Sensing
title_fullStr Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical Sensing
title_full_unstemmed Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical Sensing
title_short Dual-Valence Copper Nanostructures with Cu<sup>+</sup>/Cu<sup>2+</sup> Interfaces for High-Sensitivity Glucose Electrochemical Sensing
title_sort dual valence copper nanostructures with cu sup sup cu sup 2 sup interfaces for high sensitivity glucose electrochemical sensing
topic dual-valence copper composite
interfaces
metal oxide
glucose
detection
url https://www.mdpi.com/2079-4991/14/24/2000
work_keys_str_mv AT zhipengyu dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing
AT pengxuyan dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing
AT yileisheng dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing
AT chengweizhang dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing
AT zhunqiao dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing
AT qikuifan dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing
AT chuncaikong dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing
AT zhimaoyang dualvalencecoppernanostructureswithcusupsupcusup2supinterfacesforhighsensitivityglucoseelectrochemicalsensing