Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and Argentina

Caregivers are important stakeholders in epilepsy management, and effective communication between healthcare providers (HCPs) and caregivers is needed to optimize patient well-being. The study aimed to identify and evaluate the burden of epilepsy care across the age spectrum from the caregiver’s per...

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Main Authors: Ioannis Karakis, Santiago Flesler, Sanman Ghorpade, Rio Carla Pineda, Kalpesh Joshi, James Cooper, Shilpa Patkar, Andrea Schulz, Savita Bakhshi Anand, Nicola Barnes
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Epilepsy & Behavior Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589986424000935
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author Ioannis Karakis
Santiago Flesler
Sanman Ghorpade
Rio Carla Pineda
Kalpesh Joshi
James Cooper
Shilpa Patkar
Andrea Schulz
Savita Bakhshi Anand
Nicola Barnes
author_facet Ioannis Karakis
Santiago Flesler
Sanman Ghorpade
Rio Carla Pineda
Kalpesh Joshi
James Cooper
Shilpa Patkar
Andrea Schulz
Savita Bakhshi Anand
Nicola Barnes
author_sort Ioannis Karakis
collection DOAJ
description Caregivers are important stakeholders in epilepsy management, and effective communication between healthcare providers (HCPs) and caregivers is needed to optimize patient well-being. The study aimed to identify and evaluate the burden of epilepsy care across the age spectrum from the caregiver’s perspective and understand the perception and management of caregiver burden, including drivers of decision-making in clinical practice, by HCPs. This was a cross-sectional survey of unpaid caregivers of persons with epilepsy (PWE) and HCPs treating PWE. A total of 200 caregivers (China and Taiwan: n = 65/200, 32.5 % each; Argentina: n = 70/200, 35.0 %), and 200 HCPs (China and Taiwan: n = 70/200, 35.0 % each; Argentina: n = 60/200, 30.0 %) participated. Caregivers commonly experienced emotional impacts including anxiety (58.5 %), depression (45.5 %), work/school productivity loss (40.0 %), reduced working hours (40.0 %), or financial stress (24.5 %). HCPs identified several challenges faced by caregivers care, such as fatigue (85.0 %), poor-quality sleep (68.0 %), emotional impacts and stress (61.5 % each), anxiety (57.0 %), and worry about the patient’s future prospects (54.0 %) (e.g., health status (56.5 %), loss of work productivity/career opportunities (50.5 %), worsening of the condition (47.0 %), seizure frequency (46.0 %), and impact on quality of life (46.0 %)). Caregivers for PWE reported emotional, work-related, physical, financial, and social impacts. HCPs recognized similar findings and alignment with the caregiving burden. This study identifies gaps in caregiver support and can be a basis for future initiatives to improve the needs of caregivers and gaps in family-HCP communication so that they can partner with HCPs in the care of PWE.
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spelling doaj-art-1cdec28bb0574f3692b914f0abc880a22025-08-20T02:01:04ZengElsevierEpilepsy & Behavior Reports2589-98642025-06-013010073610.1016/j.ebr.2024.100736Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and ArgentinaIoannis Karakis0Santiago Flesler1Sanman Ghorpade2Rio Carla Pineda3Kalpesh Joshi4James Cooper5Shilpa Patkar6Andrea Schulz7Savita Bakhshi Anand8Nicola Barnes9Department of Neurology, Emory University School of Medicine, 12 Executive Park Dr NE, Atlanta, GA 30322, USA; Department of Neurology, University of Crete School of Medicine, Heraklion 71003, Crete, GreeceConsultant Pediatric Neurologist, Hospital Aleman, CINNES, Av. Pueyrredón 1640, Ciudad de Buenos Aires, ArgentinaGlobal Medical Affairs, GSK, Dr. Annie Besant Road, Mumbai 400030, Maharashtra, India; Corresponding author.Global Medical Affairs, GSK, 23rd Floor, The Finance Centre, 26th Street, Taguig, 1634 Metro Manila, PhilippinesGlobal Medical Affairs, GSK, Dr. Annie Besant Road, Mumbai 400030, Maharashtra, IndiaGlobal Medical Affairs, GSK, 980 Great West Rd, London TW8 9GS, UKGlobal Medical Affairs, GSK, Dr. Annie Besant Road, Mumbai 400030, Maharashtra, IndiaEvidera, Inc., 7101 Wisconsin Ave # 1400, Bethesda, MD 20814, USAEvidera, Inc., The Ark, 2nd Floor, 201 Talgarth Road, London W6 8BJ, UKEvidera, Inc., The Ark, 2nd Floor, 201 Talgarth Road, London W6 8BJ, UKCaregivers are important stakeholders in epilepsy management, and effective communication between healthcare providers (HCPs) and caregivers is needed to optimize patient well-being. The study aimed to identify and evaluate the burden of epilepsy care across the age spectrum from the caregiver’s perspective and understand the perception and management of caregiver burden, including drivers of decision-making in clinical practice, by HCPs. This was a cross-sectional survey of unpaid caregivers of persons with epilepsy (PWE) and HCPs treating PWE. A total of 200 caregivers (China and Taiwan: n = 65/200, 32.5 % each; Argentina: n = 70/200, 35.0 %), and 200 HCPs (China and Taiwan: n = 70/200, 35.0 % each; Argentina: n = 60/200, 30.0 %) participated. Caregivers commonly experienced emotional impacts including anxiety (58.5 %), depression (45.5 %), work/school productivity loss (40.0 %), reduced working hours (40.0 %), or financial stress (24.5 %). HCPs identified several challenges faced by caregivers care, such as fatigue (85.0 %), poor-quality sleep (68.0 %), emotional impacts and stress (61.5 % each), anxiety (57.0 %), and worry about the patient’s future prospects (54.0 %) (e.g., health status (56.5 %), loss of work productivity/career opportunities (50.5 %), worsening of the condition (47.0 %), seizure frequency (46.0 %), and impact on quality of life (46.0 %)). Caregivers for PWE reported emotional, work-related, physical, financial, and social impacts. HCPs recognized similar findings and alignment with the caregiving burden. This study identifies gaps in caregiver support and can be a basis for future initiatives to improve the needs of caregivers and gaps in family-HCP communication so that they can partner with HCPs in the care of PWE.http://www.sciencedirect.com/science/article/pii/S2589986424000935EpilepsyCaregiverHealth care providersBurden
spellingShingle Ioannis Karakis
Santiago Flesler
Sanman Ghorpade
Rio Carla Pineda
Kalpesh Joshi
James Cooper
Shilpa Patkar
Andrea Schulz
Savita Bakhshi Anand
Nicola Barnes
Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and Argentina
Epilepsy & Behavior Reports
Epilepsy
Caregiver
Health care providers
Burden
title Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and Argentina
title_full Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and Argentina
title_fullStr Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and Argentina
title_full_unstemmed Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and Argentina
title_short Caregiver burden and healthcare providers perspectives in epilepsy: An observational study in China, Taiwan, and Argentina
title_sort caregiver burden and healthcare providers perspectives in epilepsy an observational study in china taiwan and argentina
topic Epilepsy
Caregiver
Health care providers
Burden
url http://www.sciencedirect.com/science/article/pii/S2589986424000935
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