Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium

Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium

IntroductionAzithromycin improves symptomology in various chronic airway diseases exacerbated by viral infections. However, the mechanisms underlying the apparent antiviral effects of azithromycin remain unclear.MethodsAirway epithelial cells from healthy children were cultured, expanded and differe...

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Bibliographic Details
Main Authors: Kevin Looi, Erika N. Sutanto, Thomas Iosifidis, Luke J. Berry, Anthony Kicic, Stephen M. Stick
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
airway epithelium
tight junction
human rhinovirus
azithromycin
barrier function
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1532656/full
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