Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro
Abstract Improving the quality and developmental competence of in vitro-produced (IVP) embryos is crucial for assisted reproductive technologies. Recently, we demonstrated that TLR2, an innate immune receptor, is expressed in bovine sperm and their activation improves fertilization and subsequent em...
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| Main Authors: | Dongxue Ma, Ihshan Akthar, Taiyo Hashimoto, Mohamed A. Marey, Kazuya Kusama, Kazuhiko Imakawa, Masayuki Shimada, Akio Miyamoto |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-09570-2 |
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