Discovery of novel antifungal drugs via screening repurposing libraries against Coccidioides posadasii spherule initials

ABSTRACT Coccidioidomycosis or valley fever is a treatment-limited fungal infection endemic to the alkaline deserts of North and South America for which two classes of antifungals are typically used: the polyenes and the triazoles. In light of the limited usefulness of the echinocandins and a growin...

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Bibliographic Details
Main Authors: Sarah Saeger, Kathryn West-Jeppson, Yu-Rou Liao, Althea Campuzano, Jieh-Juen Yu, Jose Lopez-Ribot, Chiung-Yu Hung
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.00205-25
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