Total Leukocyte Count in Rattus norvegicus after Duffy Binding-Like 2β-Plasmodium falciparum Erythrocyte Membrane Protein 1 Recombinant Protein Injection: The way to a Peptide-based Malaria Vaccine Development

Total Leukocyte Count in Rattus norvegicus after Duffy Binding-Like 2β-Plasmodium falciparum Erythrocyte Membrane Protein 1 Recombinant Protein Injection: The way to a Peptide-based Malaria Vaccine Development

Introduction: Severe malaria caused by Plasmodium falciparum is mediated by the P. falciparum erythrocyte membrane protein 1 (PfEMP1). It has a DBL2β domain that specifically binds to the intercellular adhesion molecule-1 (ICAM-1) receptor that lies in endothelial cells of many vital organs and is i...

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Bibliographic Details
Main Authors: Dwi Ari Santi Putri, Erma Sulistyaningsih, Irawan Fajar Kusuma, Rosita Dewi
Format: Article
Language:English
Published: Wolters Kluwer – Medknow Publications 2022-12-01
Series:Biomolecular and Health Science Journal
Subjects:
duffy binding-like domain
leukocyte
malaria vaccine candidate
protein
Online Access:https://journals.lww.com/10.4103/bhsj.bhsj_30_22
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