Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trial
Abstract Background Ni-Ti instruments with varying design features may lead to different levels of postoperative pain, which is a significant clinical concern, particularly in previously asymptomatic teeth. Therefore, the purpose of this randomized clinical trial is to compare postoperative pain fol...
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BMC
2025-04-01
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| Online Access: | https://doi.org/10.1186/s12903-025-05895-6 |
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| author | Çağla Vardar Korkman Faruk Haznedaroğlu |
| author_facet | Çağla Vardar Korkman Faruk Haznedaroğlu |
| author_sort | Çağla Vardar Korkman |
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| description | Abstract Background Ni-Ti instruments with varying design features may lead to different levels of postoperative pain, which is a significant clinical concern, particularly in previously asymptomatic teeth. Therefore, the purpose of this randomized clinical trial is to compare postoperative pain following instrumentation with TruNatomy versus ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis. Methods 90 healthy participants were randomly assigned to two groups: TruNatomy (TN) or ProTaper Next (PTN) instruments. After single-visit root canal treatments, participants were asked to rate their postoperative pain levels at 6, 12, 24, 48, and 72 h and seven days later, using the Numerical Rating Scale (NRS) through an online questionnaire. In cases of pain, 400 mg of ibuprofen was prescribed. Data from 80 participants were finally included in the analysis. Data were analyzed using the Mann-Whitney U, Friedman, and Fisher’s Chi-Square tests (p < 0.05). Results There was no statistically significant difference in postoperative pain intensity at 6, 12, 24, and 48 h and seven days between the groups (p > 0.05). At the 72-hour time point, TN group showed statistically higher postoperative pain intensity (p < 0.05). No statistically significant differences in the incidence of postoperative pain were observed at any of the time points (p > 0.05). Analgesic intake and flare-up incidence were not significantly different between the groups (p > 0.05). Conclusion Postoperative pain levels were not significantly influenced by the type of rotary Ni-Ti instrument. Both TN and PTN instruments led to low-level and similar postoperative pain intensity, minimal analgesic use, and a low incidence of flare-ups in teeth with asymptomatic apical periodontitis. Trial registration ClinicalTrials.gov ID NCT06545773, Registration Date 8 August 2024 (retrospectively registered). |
| format | Article |
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| institution | OA Journals |
| issn | 1472-6831 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
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| series | BMC Oral Health |
| spelling | doaj-art-1cc1c4ce156f41fc8c6eb9d54b1e992e2025-08-20T02:17:52ZengBMCBMC Oral Health1472-68312025-04-0125111310.1186/s12903-025-05895-6Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trialÇağla Vardar Korkman0Faruk Haznedaroğlu1Faculty of Dentistry, Department of Endodontics, Istanbul UniversityFaculty of Dentistry, Department of Endodontics, Istanbul UniversityAbstract Background Ni-Ti instruments with varying design features may lead to different levels of postoperative pain, which is a significant clinical concern, particularly in previously asymptomatic teeth. Therefore, the purpose of this randomized clinical trial is to compare postoperative pain following instrumentation with TruNatomy versus ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis. Methods 90 healthy participants were randomly assigned to two groups: TruNatomy (TN) or ProTaper Next (PTN) instruments. After single-visit root canal treatments, participants were asked to rate their postoperative pain levels at 6, 12, 24, 48, and 72 h and seven days later, using the Numerical Rating Scale (NRS) through an online questionnaire. In cases of pain, 400 mg of ibuprofen was prescribed. Data from 80 participants were finally included in the analysis. Data were analyzed using the Mann-Whitney U, Friedman, and Fisher’s Chi-Square tests (p < 0.05). Results There was no statistically significant difference in postoperative pain intensity at 6, 12, 24, and 48 h and seven days between the groups (p > 0.05). At the 72-hour time point, TN group showed statistically higher postoperative pain intensity (p < 0.05). No statistically significant differences in the incidence of postoperative pain were observed at any of the time points (p > 0.05). Analgesic intake and flare-up incidence were not significantly different between the groups (p > 0.05). Conclusion Postoperative pain levels were not significantly influenced by the type of rotary Ni-Ti instrument. Both TN and PTN instruments led to low-level and similar postoperative pain intensity, minimal analgesic use, and a low incidence of flare-ups in teeth with asymptomatic apical periodontitis. Trial registration ClinicalTrials.gov ID NCT06545773, Registration Date 8 August 2024 (retrospectively registered).https://doi.org/10.1186/s12903-025-05895-6Postoperative painRoot canal preparationApical periodontitisNiTi |
| spellingShingle | Çağla Vardar Korkman Faruk Haznedaroğlu Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trial BMC Oral Health Postoperative pain Root canal preparation Apical periodontitis NiTi |
| title | Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trial |
| title_full | Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trial |
| title_fullStr | Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trial |
| title_full_unstemmed | Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trial |
| title_short | Comparison of postoperative pain after instrumentation with TruNatomy or ProTaper Next Ni-Ti systems in mandibular molars with asymptomatic apical periodontitis: a randomized clinical trial |
| title_sort | comparison of postoperative pain after instrumentation with trunatomy or protaper next ni ti systems in mandibular molars with asymptomatic apical periodontitis a randomized clinical trial |
| topic | Postoperative pain Root canal preparation Apical periodontitis NiTi |
| url | https://doi.org/10.1186/s12903-025-05895-6 |
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