Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase

Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase

BackgroundThe SARS-CoV-2 Omicron variant is associated with milder COVID-19 symptoms than previous strains. This study analyzed alterations in natural killer (NK) cell-associated immunity dynamics in mild and moderate COVID-19 cases during the Omicron phase of the COVID-19 pandemic.MethodsWe conduct...

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Main Authors: Yukari Nishikawa, Kosuke Yamaguchi, Ma’arif Athok Shofiudin, Momone Mimura, Miyako Takata, Shu Mihara, Takeru Kawakami, Ayumu Doi, Risa Matsuda, Hiroyuki Kato, Ryo Okamoto, Kengo Mukuda, Naoki Kinoshita, Kensaku Okada, Tsuyoshi Kitaura, Masaki Nakamoto, Hisashi Noma, Yusuke Endo, Akira Yamasaki, Hiroki Chikumi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
COVID-19
Omicron variant
natural killer cells
cytokines
disease severity
ULBP2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1594296/full
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