Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control study

Background and Aims: Postanesthetic reintubation is associated with increased morbidities and mortality; however, it can be reduced with defined predictors and using a score as a tool. This study aimed to identify independent predictors and develop a reliable predictive score. Material and Methods:...

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Main Authors: Chidchanok Choovongkomol, Thidarat Ariyanuchitkul, Kongtush Choovongkomol, Vipanee Tongjapo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
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Online Access:https://journals.lww.com/10.4103/joacp.joacp_213_22
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author Chidchanok Choovongkomol
Thidarat Ariyanuchitkul
Kongtush Choovongkomol
Vipanee Tongjapo
author_facet Chidchanok Choovongkomol
Thidarat Ariyanuchitkul
Kongtush Choovongkomol
Vipanee Tongjapo
author_sort Chidchanok Choovongkomol
collection DOAJ
description Background and Aims: Postanesthetic reintubation is associated with increased morbidities and mortality; however, it can be reduced with defined predictors and using a score as a tool. This study aimed to identify independent predictors and develop a reliable predictive score. Material and Methods: A retrospective, time-matched, case control study was conducted on patients who underwent general anesthesia between October 2017 and September 2021. Using stepwise multivariable logistic regression analysis, predictors were determined and the predictive score was developed and validated. Results: Among 230 patients, 46 were in the reintubated group. Significant independent predictors included age >65 years (odds ratio [OR] 2.96 [95% confidence interval {CI} 1.23, 7.10]), the American Society of Anesthesiologists physical status III–IV (OR 6.60 [95%CI 2.50 17.41]), body mass index (BMI) ≥30 kg/m2 (OR 4.91 [95% CI 1.55, 15.51]), and head and neck surgery (OR 4.35 [95% CI 1.46, 12.87]). The predictive model was then developed with an area under the receiver operating characteristic curve (AUC) of 0.84 (95% CI 0.78, 0.90). This score ranged from 0 to 29 and was classified into three subcategories for clinical practicability, in which the positive predictive values were 6.01 (95% CI 2.63, 11.50) for low risk, 18.64 (95% CI 9.69, 30.91) for moderate risk, and 71.05 (95% CI 54.09, 84.58) for high risk. Conclusion: The independent predictors for postanesthetic reintubation according to this simplified risk-based scoring system designed to aid anesthesiologists before extubation were found to be advanced age, higher American Society of Anesthesiologists physical status, obesity, and head and neck surgery.
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spelling doaj-art-1cb6e4012e1847dd85fbcd0e11e7101d2025-08-20T01:58:27ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852024-01-0140112012610.4103/joacp.joacp_213_22Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control studyChidchanok ChoovongkomolThidarat AriyanuchitkulKongtush ChoovongkomolVipanee TongjapoBackground and Aims: Postanesthetic reintubation is associated with increased morbidities and mortality; however, it can be reduced with defined predictors and using a score as a tool. This study aimed to identify independent predictors and develop a reliable predictive score. Material and Methods: A retrospective, time-matched, case control study was conducted on patients who underwent general anesthesia between October 2017 and September 2021. Using stepwise multivariable logistic regression analysis, predictors were determined and the predictive score was developed and validated. Results: Among 230 patients, 46 were in the reintubated group. Significant independent predictors included age >65 years (odds ratio [OR] 2.96 [95% confidence interval {CI} 1.23, 7.10]), the American Society of Anesthesiologists physical status III–IV (OR 6.60 [95%CI 2.50 17.41]), body mass index (BMI) ≥30 kg/m2 (OR 4.91 [95% CI 1.55, 15.51]), and head and neck surgery (OR 4.35 [95% CI 1.46, 12.87]). The predictive model was then developed with an area under the receiver operating characteristic curve (AUC) of 0.84 (95% CI 0.78, 0.90). This score ranged from 0 to 29 and was classified into three subcategories for clinical practicability, in which the positive predictive values were 6.01 (95% CI 2.63, 11.50) for low risk, 18.64 (95% CI 9.69, 30.91) for moderate risk, and 71.05 (95% CI 54.09, 84.58) for high risk. Conclusion: The independent predictors for postanesthetic reintubation according to this simplified risk-based scoring system designed to aid anesthesiologists before extubation were found to be advanced age, higher American Society of Anesthesiologists physical status, obesity, and head and neck surgery.https://journals.lww.com/10.4103/joacp.joacp_213_22airway extubationairway managementanesthesia recovery periodsintubationpredict modelprognostic
spellingShingle Chidchanok Choovongkomol
Thidarat Ariyanuchitkul
Kongtush Choovongkomol
Vipanee Tongjapo
Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control study
Journal of Anaesthesiology Clinical Pharmacology
airway extubation
airway management
anesthesia recovery periods
intubation
predict model
prognostic
title Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control study
title_full Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control study
title_fullStr Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control study
title_full_unstemmed Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control study
title_short Independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia: A time-matched, case control study
title_sort independent predictors and clinical predictive score of postanesthetic reintubation after general anesthesia a time matched case control study
topic airway extubation
airway management
anesthesia recovery periods
intubation
predict model
prognostic
url https://journals.lww.com/10.4103/joacp.joacp_213_22
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AT kongtushchoovongkomol independentpredictorsandclinicalpredictivescoreofpostanestheticreintubationaftergeneralanesthesiaatimematchedcasecontrolstudy
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