Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports
Lineage switch is a rare phenomenon in which a transition from lymphoid to myeloid was observed in relapse of acute leukemia, or vice versa. This paper presents the four clinical case reports of acute lymphoblastic leukemia with MLL gene rearrangement (KMT2A) with myeloid phenotype in relapse.
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| Format: | Article |
| Language: | Russian |
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ABV-press
2016-08-01
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| Series: | Онкогематология |
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| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/193 |
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| author | E. A. Zerkalenkova O. I. Illarionova A. N. Kazakova N. I. Ponomareva L. V. Baydun E. Yu. Osipova M. E. Dubrovina A. M. Popov T. V. Konyukhova S. A. Plyasunova N. V. Myakova A. A. Maschan Yu. V. Olshanskaya |
| author_facet | E. A. Zerkalenkova O. I. Illarionova A. N. Kazakova N. I. Ponomareva L. V. Baydun E. Yu. Osipova M. E. Dubrovina A. M. Popov T. V. Konyukhova S. A. Plyasunova N. V. Myakova A. A. Maschan Yu. V. Olshanskaya |
| author_sort | E. A. Zerkalenkova |
| collection | DOAJ |
| description | Lineage switch is a rare phenomenon in which a transition from lymphoid to myeloid was observed in relapse of acute leukemia, or vice versa. This paper presents the four clinical case reports of acute lymphoblastic leukemia with MLL gene rearrangement (KMT2A) with myeloid phenotype in relapse. |
| format | Article |
| id | doaj-art-1cb2879f77984511ab1e04d6a383de28 |
| institution | Kabale University |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj-art-1cb2879f77984511ab1e04d6a383de282025-08-20T03:35:33ZrusABV-pressОнкогематология1818-83462413-40232016-08-01112212910.17650/1818-8346-2016-11-2-21-29196Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reportsE. A. Zerkalenkova0O. I. Illarionova1A. N. Kazakova2N. I. Ponomareva3L. V. Baydun4E. Yu. Osipova5M. E. Dubrovina6A. M. Popov7T. V. Konyukhova8S. A. Plyasunova9N. V. Myakova10A. A. Maschan11Yu. V. Olshanskaya12Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Children Clinical Hospital, 119571 Moscow, Leninskiy pr., 117Russian Children Clinical Hospital, 119571 Moscow, Leninskiy pr., 117Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Lineage switch is a rare phenomenon in which a transition from lymphoid to myeloid was observed in relapse of acute leukemia, or vice versa. This paper presents the four clinical case reports of acute lymphoblastic leukemia with MLL gene rearrangement (KMT2A) with myeloid phenotype in relapse.https://oncohematology.abvpress.ru/ongm/article/view/193acute lymphoblastic leukemiaacute myeloid leukemialineage switchkmt2a gene rearrangementimmunophenotyping |
| spellingShingle | E. A. Zerkalenkova O. I. Illarionova A. N. Kazakova N. I. Ponomareva L. V. Baydun E. Yu. Osipova M. E. Dubrovina A. M. Popov T. V. Konyukhova S. A. Plyasunova N. V. Myakova A. A. Maschan Yu. V. Olshanskaya Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports Онкогематология acute lymphoblastic leukemia acute myeloid leukemia lineage switch kmt2a gene rearrangement immunophenotyping |
| title | Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports |
| title_full | Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports |
| title_fullStr | Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports |
| title_full_unstemmed | Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports |
| title_short | Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports |
| title_sort | lineage switch in relapse of acute leukemia with rearrangement of mll gene kmt2a literature review and case reports |
| topic | acute lymphoblastic leukemia acute myeloid leukemia lineage switch kmt2a gene rearrangement immunophenotyping |
| url | https://oncohematology.abvpress.ru/ongm/article/view/193 |
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