Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes

Structural modification of organic molecule has considerable biological relevance. Further, coordination of a biomolecules to the metal ions significantly alters the effectiveness of the biomolecules. In view of the antimicrobial activity ligand [bis-(2-aminobenzaldehyde)] malonoyl dihydrazone], met...

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Main Authors: R. Rajavel, M. Senthil Vadivu, C. Anitha
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2008/583487
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author R. Rajavel
M. Senthil Vadivu
C. Anitha
author_facet R. Rajavel
M. Senthil Vadivu
C. Anitha
author_sort R. Rajavel
collection DOAJ
description Structural modification of organic molecule has considerable biological relevance. Further, coordination of a biomolecules to the metal ions significantly alters the effectiveness of the biomolecules. In view of the antimicrobial activity ligand [bis-(2-aminobenzaldehyde)] malonoyl dihydrazone], metal complexes with Cu(II), Ni(II), Zn(II) and oxovanadium(IV) have been synthesized and found to be potential antimicrobial agents. An attempt is also made to correlate the biological activities with geometry of the complexes. The complexes have been characterized by elemental analysis, molar conductance, spectra and cyclicvoltammetric measurements. The structural assessment of the complexes has been carried out based on electronic, infrared and molar conductivity values.
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spelling doaj-art-1cad62ea1cdc4422a85e2a50efcdf7192025-08-20T03:54:37ZengWileyE-Journal of Chemistry0973-49452090-98102008-01-015362062610.1155/2008/583487Synthesis, Physical Characterization and Biological Activity of Some Schiff Base ComplexesR. Rajavel0M. Senthil Vadivu1C. Anitha2Department of Chemistry, Periyar University, Salem-636011, Tamilnadu, IndiaDepartment of Chemistry, Periyar University, Salem-636011, Tamilnadu, IndiaDepartment of Chemistry, Periyar University, Salem-636011, Tamilnadu, IndiaStructural modification of organic molecule has considerable biological relevance. Further, coordination of a biomolecules to the metal ions significantly alters the effectiveness of the biomolecules. In view of the antimicrobial activity ligand [bis-(2-aminobenzaldehyde)] malonoyl dihydrazone], metal complexes with Cu(II), Ni(II), Zn(II) and oxovanadium(IV) have been synthesized and found to be potential antimicrobial agents. An attempt is also made to correlate the biological activities with geometry of the complexes. The complexes have been characterized by elemental analysis, molar conductance, spectra and cyclicvoltammetric measurements. The structural assessment of the complexes has been carried out based on electronic, infrared and molar conductivity values.http://dx.doi.org/10.1155/2008/583487
spellingShingle R. Rajavel
M. Senthil Vadivu
C. Anitha
Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes
E-Journal of Chemistry
title Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes
title_full Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes
title_fullStr Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes
title_full_unstemmed Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes
title_short Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes
title_sort synthesis physical characterization and biological activity of some schiff base complexes
url http://dx.doi.org/10.1155/2008/583487
work_keys_str_mv AT rrajavel synthesisphysicalcharacterizationandbiologicalactivityofsomeschiffbasecomplexes
AT msenthilvadivu synthesisphysicalcharacterizationandbiologicalactivityofsomeschiffbasecomplexes
AT canitha synthesisphysicalcharacterizationandbiologicalactivityofsomeschiffbasecomplexes