Vascular remodeling in arteriovenous fistula treated with PDE5A inhibitors

Vascular remodeling in arteriovenous fistula treated with PDE5A inhibitors

Abstract The arteriovenous fistula (AVF) is the lifeline for hemodialysis patients. However, there are currently no effective therapies promoting AVF maturation. AVF dilation by smooth muscle cell relaxation, through increased cyclic guanosine monophosphate (cGMP), is one potential mechanism to impr...

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Bibliographic Details
Main Authors: Maheshika Somarathna, Hannah Northrup, Kevin Ingle, Tatyana Isayeva‐Waldrop, Nguyen Thuy Nhu Nguyen, Bailey Lose, Yan‐Ting Shiu, Timmy Lee
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Physiological Reports
Subjects:
arteriovenous fistula
hemodialysis
PDE5A
sildenafil
vascular access
vascular remodeling
Online Access:https://doi.org/10.14814/phy2.70331
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