Refining malaria diagnosis in high-transmission areas: a dual-approach with rapid diagnostic tests (RDTs) and dbPCR-NALFIA

Refining malaria diagnosis in high-transmission areas: a dual-approach with rapid diagnostic tests (RDTs) and dbPCR-NALFIA

Abstract Background Malaria rapid diagnostic tests (RDTs) are an essential tool in managing febrile illnesses in endemic settings. However, persisting parasite antigen after treatment or spontaneous remission, which can be detected by histidine-rich protein 2 (HRP2)-based RDT or Plasmodium lactate d...

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Bibliographic Details
Main Authors: Diane Yirgnur Some, Francois Kiemde, Hermann Sorgho, Marc Christian Tahita, Antonia Windkouni Bere, Abdoulaye Ouedraogo, Souleymane Vivien Banao, Kouadjo Bagre, Gérémie Djiri, Georges Some, Toussaint Rouamba, Yeri Esther Hien, Aly Savadogo, Henk D. F. H. Schallig, Halidou Tinto
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Malaria Journal
Subjects:
Malaria diagnosis
Microscopy
RDTs
DbPCR-NALFIA
Sequential algorithm
Online Access:https://doi.org/10.1186/s12936-025-05500-9
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