Investigating glutamatergic mechanism in attention and impulse control using rats in a modified 5-choice serial reaction time task.

The 5-choice serial reaction time task (5CSRTT) has been widely used to study attention and impulse control in rodents. In order to mimic cognitive impairments in psychiatry, one approach has been to use acute administration of NMDA antagonists. This disruption in glutamatergic transmission leads to...

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Bibliographic Details
Main Authors: Abigail Benn, Emma S J Robinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115374
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