Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant Application

To develop the corrosion resistance and improve the biological performance of a titanium implant (Ti6Al4V alloy), a series of mineral (M = Zn and Mg)-substituted hydroxyapatite (MHA), chitosan-MHA (CS-MHA), halloysite nanotube-MHA (HNT-MHA), and HNT-CS-MHA composite coatings were fabricated on the a...

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Main Authors: Manickam Chozhanathmisra, Kannaiyan Pandian, Dharman Govindaraj, Palanisamy Karthikeyan, Liviu Mitu, Rangappan Rajavel
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2019/7472058
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author Manickam Chozhanathmisra
Kannaiyan Pandian
Dharman Govindaraj
Palanisamy Karthikeyan
Liviu Mitu
Rangappan Rajavel
author_facet Manickam Chozhanathmisra
Kannaiyan Pandian
Dharman Govindaraj
Palanisamy Karthikeyan
Liviu Mitu
Rangappan Rajavel
author_sort Manickam Chozhanathmisra
collection DOAJ
description To develop the corrosion resistance and improve the biological performance of a titanium implant (Ti6Al4V alloy), a series of mineral (M = Zn and Mg)-substituted hydroxyapatite (MHA), chitosan-MHA (CS-MHA), halloysite nanotube-MHA (HNT-MHA), and HNT-CS-MHA composite coatings were fabricated on the anodized titanium alloy by electrodeposition. The surface morphology and cross section of various coated composites were investigated by high-resolution scanning electron microscopy (HR-SEM). Furthermore, the functional groups and phase structure of the composite coatings were investigated by Fourier transform infrared spectroscopy (FTIR) and X-ray diffractometry (XRD). Corrosion behaviors of the composite coatings were also investigated by polarization and impedance spectroscopy (EIS). Moreover, the cell-material interaction of the composite coating was observed in vitro with human osteoblast MG63 cells for cell proliferation at 1, 4, and 7 days of incubation. Consequently, HNT-CS-MHA-Ti may have potential applications in the field of orthopedic and dental implants.
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institution OA Journals
issn 2090-9063
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language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Journal of Chemistry
spelling doaj-art-1c960bfdfd684493ba2f1257efa1986b2025-08-20T02:01:45ZengWileyJournal of Chemistry2090-90632090-90712019-01-01201910.1155/2019/74720587472058Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant ApplicationManickam Chozhanathmisra0Kannaiyan Pandian1Dharman Govindaraj2Palanisamy Karthikeyan3Liviu Mitu4Rangappan Rajavel5Department of Chemistry, Periyar University, Salem 636011, Tamilnadu, IndiaDepartment of Inorganic Chemistry, University of Madras, Guindy Campus, Chennai 600025, Tamilnadu, IndiaDepartment of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625021, IndiaDepartment of Chemistry, Periyar University Constituent College of Arts and Science Idappadi, Salem 637102, Tamilnadu, IndiaDepartment of Physics & Chemistry, University of Pitesti, Pitesti 110040, RomaniaDepartment of Chemistry, Periyar University, Salem 636011, Tamilnadu, IndiaTo develop the corrosion resistance and improve the biological performance of a titanium implant (Ti6Al4V alloy), a series of mineral (M = Zn and Mg)-substituted hydroxyapatite (MHA), chitosan-MHA (CS-MHA), halloysite nanotube-MHA (HNT-MHA), and HNT-CS-MHA composite coatings were fabricated on the anodized titanium alloy by electrodeposition. The surface morphology and cross section of various coated composites were investigated by high-resolution scanning electron microscopy (HR-SEM). Furthermore, the functional groups and phase structure of the composite coatings were investigated by Fourier transform infrared spectroscopy (FTIR) and X-ray diffractometry (XRD). Corrosion behaviors of the composite coatings were also investigated by polarization and impedance spectroscopy (EIS). Moreover, the cell-material interaction of the composite coating was observed in vitro with human osteoblast MG63 cells for cell proliferation at 1, 4, and 7 days of incubation. Consequently, HNT-CS-MHA-Ti may have potential applications in the field of orthopedic and dental implants.http://dx.doi.org/10.1155/2019/7472058
spellingShingle Manickam Chozhanathmisra
Kannaiyan Pandian
Dharman Govindaraj
Palanisamy Karthikeyan
Liviu Mitu
Rangappan Rajavel
Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant Application
Journal of Chemistry
title Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant Application
title_full Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant Application
title_fullStr Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant Application
title_full_unstemmed Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant Application
title_short Halloysite Nanotube-Reinforced Ion-Incorporated Hydroxyapatite-Chitosan Composite Coating on Ti-6Al-4 V Alloy for Implant Application
title_sort halloysite nanotube reinforced ion incorporated hydroxyapatite chitosan composite coating on ti 6al 4 v alloy for implant application
url http://dx.doi.org/10.1155/2019/7472058
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