Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15

Two groups of PLGA specimens with different geometries (notched and unnotched) were injection molded under two melting temperatures and flow rates. The mechanical properties, morphology at the fracture surface, and residual stresses were evaluated for both processing conditions. The morphology of th...

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Main Authors: Liliane Pimenta de Melo, Gean Vitor Salmoria, Eduardo Alberto Fancello, Carlos Rodrigo de Mello Roesler
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2017/6435076
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author Liliane Pimenta de Melo
Gean Vitor Salmoria
Eduardo Alberto Fancello
Carlos Rodrigo de Mello Roesler
author_facet Liliane Pimenta de Melo
Gean Vitor Salmoria
Eduardo Alberto Fancello
Carlos Rodrigo de Mello Roesler
author_sort Liliane Pimenta de Melo
collection DOAJ
description Two groups of PLGA specimens with different geometries (notched and unnotched) were injection molded under two melting temperatures and flow rates. The mechanical properties, morphology at the fracture surface, and residual stresses were evaluated for both processing conditions. The morphology of the fractured surfaces for both specimens showed brittle and smooth fracture features for the majority of the specimens. Fracture images of the notched specimens suggest that the surface failure mechanisms are different from the core failure. Polarized light techniques indicated birefringence in all specimens, especially those molded with lower temperature, which suggests residual stress due to rapid solidification. DSC analysis confirmed the existence of residual stress in all PLGA specimens. The specimens molded using the lower injection temperature and the low flow rate presented lower loss tangent values according to the DMA and higher residual stress as shown by DSC, and the photoelastic analysis showed extensive birefringence.
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institution OA Journals
issn 1687-8787
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language English
publishDate 2017-01-01
publisher Wiley
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series International Journal of Biomaterials
spelling doaj-art-1c904cb7a48e4660b8bd7d19ae7c7e192025-08-20T02:01:45ZengWileyInternational Journal of Biomaterials1687-87871687-87952017-01-01201710.1155/2017/64350766435076Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15Liliane Pimenta de Melo0Gean Vitor Salmoria1Eduardo Alberto Fancello2Carlos Rodrigo de Mello Roesler3Biomechanical Engineering Laboratory (LEBm), University Hospital (HU), Federal University of Santa Catarina, 88040-900 Florianópolis, SC, BrazilBiomechanical Engineering Laboratory (LEBm), University Hospital (HU), Federal University of Santa Catarina, 88040-900 Florianópolis, SC, BrazilBiomechanical Engineering Laboratory (LEBm), University Hospital (HU), Federal University of Santa Catarina, 88040-900 Florianópolis, SC, BrazilBiomechanical Engineering Laboratory (LEBm), University Hospital (HU), Federal University of Santa Catarina, 88040-900 Florianópolis, SC, BrazilTwo groups of PLGA specimens with different geometries (notched and unnotched) were injection molded under two melting temperatures and flow rates. The mechanical properties, morphology at the fracture surface, and residual stresses were evaluated for both processing conditions. The morphology of the fractured surfaces for both specimens showed brittle and smooth fracture features for the majority of the specimens. Fracture images of the notched specimens suggest that the surface failure mechanisms are different from the core failure. Polarized light techniques indicated birefringence in all specimens, especially those molded with lower temperature, which suggests residual stress due to rapid solidification. DSC analysis confirmed the existence of residual stress in all PLGA specimens. The specimens molded using the lower injection temperature and the low flow rate presented lower loss tangent values according to the DMA and higher residual stress as shown by DSC, and the photoelastic analysis showed extensive birefringence.http://dx.doi.org/10.1155/2017/6435076
spellingShingle Liliane Pimenta de Melo
Gean Vitor Salmoria
Eduardo Alberto Fancello
Carlos Rodrigo de Mello Roesler
Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15
International Journal of Biomaterials
title Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15
title_full Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15
title_fullStr Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15
title_full_unstemmed Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15
title_short Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15
title_sort influence of processing conditions on the mechanical behavior and morphology of injection molded poly lactic co glycolic acid 85 15
url http://dx.doi.org/10.1155/2017/6435076
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AT eduardoalbertofancello influenceofprocessingconditionsonthemechanicalbehaviorandmorphologyofinjectionmoldedpolylacticcoglycolicacid8515
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