Effects of Incorporating Carboxymethyl Chitosan into PMMA Bone Cement Containing Methotrexate.
Treatment of bone metastases usually includes surgical resection with local filling of methotrexate (MTX) in polymethyl methacrylate (PMMA) cement. We investigated whether incorporating carboxymethyl chitosan (CMCS) in MTX-PMMA cement might overcome disadvantages associated with MTX. To determine th...
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| Main Authors: | Bo-Ming Liu, Ming Li, Bao-Sheng Yin, Ji-Yang Zou, Wei-Guo Zhang, Shou-Yu Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144407&type=printable |
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